DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20211138

Fetomaternal outcome in eclampsia

Madhumita Roy, Laishram Ayingbi, Telen Thangkhojam Kom, Usharani Akoijam, Papiya Paul, L. Ranjit Singh, Rahul Das

Abstract


Background: Eclampsia is the third most common cause of maternal mortality, after haemorrhage and infection in the developing countries. Majority of cases of eclampsia are young primigravidas. The reduction in both maternal and perinatal morbidity and mortality remains the yard stick of success in the management of eclampsia.

Methods: A hospital based analytical cross-sectional study was conducted among the pregnant women with eclampsia admitted in the department of Obstetrics and Gynecology in Regional Institute of Medical Sciences, Imphal. The study was conducted for a period of one and half years from September 2018 to March 2020.

Results: Fifty-five (55) patients in the age group between 21 and 25 years constitute the maximum percentage of eclampsia (67.3%). Forty-five (81.8%) cases were antepartum eclampsia, 2 (3.6%) were intrapartum eclampsia and 8 (14.5%) cases were postpartum eclampsia. Majority (78.2%) of the cases were primigravidae, which is comparable to other studies. As much as 23 (41.8%) of the cases presented at 32-37 weeks period of gestation. There were two maternal deaths (3.6%) due to eclampsia related complications. There were 13 (21.7%) perinatal deaths in this study, out of which 10 (16.7%) were still births and 3(5%) were early neonatal deaths.

Conclusions: Eclampsia is still an important obstetric emergency in the community contributing to significant maternal and perinatal morbidity and mortality. Eclampsia may not develop de novo and as such, it is not always a preventable condition. Early detection and prompt intervention of complications is vital to ensure a healthy outcome for both mother and baby.


Keywords


Cross sectional study, Eclampsia, Pre-eclampsia

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References


Chesley LC. A short history of eclampsia. Obstet Gynecol. 1974;43:500-602.

Singh BM, Mishra R. Hypertensive disorders. Mishra R, edr. Ian Donalds Practical Obstetric problem. 7th edn. BI Publications Pvt. Ltd: New Delhi; 2014:142-175.

Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Spongy CY. Williams Obstetrics. 23rd edn. New York: McGraw-Hill; 2010.

Sibai BM, Drekker G, Kupferminc M. Preeclampsia. Lancet. 2005;365(9461):785-99.

Andersgaard AB, Herbst A, Johansen M, Ivarsson A, Ingemarsson I, Langhoff-Roos J, et al. Eclampsia in Scandinavia: incidence, substandard care, and potentially preventable cases. Acta Obstet Gynecol Scand. 2006;85(8):929-36.

Swain S, Ohha KN, Prakash A. Maternal and perinatal mortality due to eclampsia. Indian Pediatr. 1993;30(6):771-3.

Mynemba J. Magnesium sulphate for eclampsia: putting evidence into clinical practice. Cent Afr J Med. 2000;46(6):166-9.

Educational material for teachers of midwifery. Managing Postpartum heamorrhage. 2nd edn. World health Organization; 2008:1-131.

Sibai BM. Diagnosis, prevention and management of eclampsia. Obstet Gynecol. 2005;105(2):402-10.

Douglas KA, Redman CW. Eclampsia in the United Kingdom. BMJ. 1994;309(6966):1395-400.

Sarma HK, Talukdar B. Eclampsia: a clinical prospective study in a referral hospital. J Obstet Gynaecol Barpeta. 2014;1(1):57-61.

Rayamajhi AK, Uprety D, Agrawal A, Pokhrel H. Fetomaternal outcome in eclampsia. J Nepal Med Assoc. 2003;42:341-5.

Singh A, Chawla S, Pandey D, Jahan N, Anwar A. Fetomaternal outcome in cases of pre-eclampsia in a tertiary care referral hospital in Delhi, India: a retrospective analysis. Int J Sci Stud. 2016;4(2):100-3.

Sinha M, Sinha SK. Perinatal and Maternal outcomes of Eclampsia in Darbhanga District, Bihar, India. Int J Contemp Med Res. 2018;5(2):1-4.

Sultana A, Koli LNB, Sayeeda S. Clinical study on risk factors and fetomaternal outcome of severe preeclampsia in Bangabandhu Sheikh Mujib Medical University. CMOSHMC J. 2018;17(1):23-8.

Pannu D, Das B, Hazari P, Shilpa. Maternal and perinatal outcome in eclampsia and factors affecting the outcome: a study in North Indian population. Int J Reprod Contracept Obstet Gynecol 2014;3:347-51.

Dutta DC. Hypertensive disorder in pregnancy. In: Dutta DC, edr. Textbook of obstetrics including perinatology and contraception. 7th edn. New Delhi: Jaypee brothers medical publishers (p) ltd; 2013:219-40.

Carlo WA. The fetus and neonatal infant. In: Kliegman RM, Stanton BF, Geme JWS, Schor NF, eds. Nelson Text Book of Pediatrics. 1st edn. South Asia: Reed Elsevier India Private Limited; 2016:789-800.

Aabidha PM, Cherian AG, Paul E, Helan J. Maternal and fetal outcome in pre-eclampsia in a secondary care hospital in South India. J Fam Med Prim Care. 2015;4(2):257-60.

Begum MR, Begum A, Quadir E, Akhter S, Shamsuddin L. Eclampsia: still a problem in Bangladesh. Med Gen Med. 2004;6(4):52.

Prabhakar G, Shinde MA, Jadhav CA. Clinical study of eclampsia patients at DR. V M. Government Medical Collage Solapur, India. IOSR-J Dent Med Sci. 2015;13(7):10-6.

Pradeep MR, Shivanna L. Retrospective study of eclampsia in a teaching hospital. Int J Recent Trends Sci Tech. 2013;8(3):171-3.

Choudhary P. Eclampsia: A hospital based retrospective study. Kathmandu Univ Med J. 2003;1(4):237-41.

Katz VL, Farmer R, Kuller JA. Pre-eclampsia into eclampsia: towards a new paradigm. Am J Obstet Gynecol 2000;182:1389-96.

Onuh SO, Aisien AO. Maternal and fetal outcome in eclamptic patients in Benin City, Nigeria. J Obstet Gynaecol. 2004;24(7):765-8.

Singh S, Behera AK. Eclampsia in Eastern India: incidence, demographic profile and response to three different anticonvulsant regimes of magnesium sulphate. Internet J Gynecol Obstet. 2011;15(2):1-8.

Ndaboine EM, Kihunrwa A, Rumanyika R, Beatrice IMH, Massinde AN. Maternal and perinatal outcomes among eclamptic patients admitted to Bugando medical centre, Mwanza, Tanzania. Afr J Reprod Health. 2012;16(1):35.

Chappell L, Enye S, Seed P, Briley A, Poston L, Shennan A. Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension. Hypertension. 2008;51:1002-9.

Ray JG, Burrows RF, Burrows EA, Vermeulen MJ. MOS HIP: McMaster outcome study of hypertension in pregnancy. Early Hum Dev. 2001;64:129-43.

Ghimire S. Eclampsia: feto-maternal outcomes in a tertiary care centre in Eastern Nepal. J Nepal Med Assoc. 2016;54(201):24-8.

Duhan L, Nanda S, Dahiya P, Chaudhary S. Sociodemographic profiling and study of maternal and perinatal outcome in patients suffering from eclampsia. Int J Reprod Contracept Obstet Gynecol. 2016;5(6):1870-3.

Pokharel N, Shrestha M, Regmi M. Maternal, fetal and new born outcomes in pre-eclampsia and eclampsia: a hospital based study. Health Renais. 2014;12(2):106-10.

Raji C, Poovathi M, Nithya D. Prospective study of fetomaternal outcome in eclampsia in a tertiary care hospital. Int J Repord Contracept Obstet Gynecol. 2016;5(12):4329-34.

Okoror CEM. Maternal andperinatal outcome in women with eclampsia: a retrospective study at the University of Benin Teaching Hospital. Int J Repord Contracept Obstet Gynecol. 2019;8:108-14.