DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20205752

Epidemiology of ectopic pregnancy at Laquintinie Douala hospital (Cameroon): prevalence survey, clinical profile, therapeutic and transfusion issues

Henri Essome, Théophile N. Nana, Gregory E. Halle, Thomas O. Egbe, Merlin Boten, Grace T. Tocki, Pascal Foumane

Abstract


Background: Pregnancy is a serious pathology of the first trimester of pregnancy and is the leading cause of death. The objective of our work was to determine the hospital prevalence of ectopic pregnancy (EP), to describe the epidemiological, clinical and therapeutic profile given the often-haemorrhagic context at Laquintinie Hospital in Douala.

Methods: We carried out a retrospective study over 10 years, from January 1st, 2007 to December 31st, 2016, using the operating theatre registers and the files of patients admitted during this period for ectopic pregnancy in the gynaecology and obstetrics department of the Laquintinie Hospital in Douala.

Results: A total of 905 cases of EP for 32,595 deliveries were recorded, for an overall incidence of 2.8%. EP mainly affected the age group of 25 to 35 (60.6%), single people (57.9%) and housewives (46.6%). The risk factors found were similar to those of cervical cancer, namely multiple sexual partners (80.4%), the precocity of sexual intercourse under 18 years (54.1%) and sexually transmitted infections (52.5%). The symptomatic triad (pelvic pain, amenorrhea and metrorrhagia) was found in 46.1% of cases with a respective order of frequency of 96.9%, 77.3% and 63.6% The management was essentially surgical by radical laparotomy (97% of cases). Two of the 07 deaths were due to religious considerations.

Conclusions: EP remains a frequent pathology in our environment with a heavy toll of tubal amputations and death.


Keywords


Death, Ectopic pregnancy, Laparotomy, Transfusion

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References


Courbiere B, Carcopino X. KB Gynécologie Obstétrique. 2012;128-139.

Madelenat P. Recommendations for clinical practice: management of ectopic pregnancy. J Gynécolobstet Biol Reprod. 2003;32.

Centers for disease control and prevention: ectopic pregnancy United States. 1992;273(7):533.

Vanitha N, Sivalingam, Duncan C, Kirk E, Lucy AS, Andrew WH. Diagnosis and management of ectopic pregnancy. J Fam Plann Reprod Health Care. 2011;37:231-40.

Randriambololona DMA, Anjaharisoaniaina NT, Rekoronirina EB, Harioly MOJ, Randriambelomanana JA, Andrianampanalinarivo RH. Ectopic pregnancy in Madagascar: 107 observations. Med Santé trop. 2012;22(4);394-7.

Meyé JF, Sima A, Olé BS, Kendjo E, Beka TE. Aspects actuels de la grossesse extra-utérine à Libreville (Gabon): à propos de 153 cas. Cahiers d’études et de recherches francophones. 2002;12(4):405-8.

Leke RJ, Goyaux N, Matsuda T, Thonneau PF. Prenancy in Africa: A population-based study. Obstet Gynecol. 2004;103:692-7.

Dohbit JS, Foumane P, Kapche MD, Mboudou ET, Doumbe M, Doh AS. Extrauterine pregnancy at the regional hospital of bafoussam: epidemiological, clinical and therapeutic aspects. Clin Mother Child Health. 2010;7(1).

Kenfack B, Noubom M, Bongoe A, Tsaledem FA, Ngono M. Ectopic pregnancy in a semi rural area in South Africa. Pan Afr Med J. 2012;13:71.

Iffy L. The role of premenstrual, post mid cycle conception in the étiology of ectopic gestation. J Obstet Gynecol Br Commonw. 1963;70:996-1000.

Coste J, Laumon B, Bremond A, Collet P, Job-Spira N. Sexually transmitted diseases as major causes of ectopic pregnancy results from a large case-control study in France. Fertil Steril. 1994;62:289-95.

Egger M, Low N, Smith GD, Lind blom B, Herrmann B. Screening for chlamydial infections and the risk of ectopic pregnancy in Sweden: ecological analysis. Br Med J. 1998;316:1776-80.

Kulp JL, Kurt TB. Ectopic pregnancy: diagnosis and management. Women's Health. 2008;4(1):79-87.

Foumane P, Mboudou ET, Mbakop S, Dohbit J.S, Belinga E, Doh A.S. La place du traitement peu ou non invasif dans la prise en charge de la grossesse extra-utérine à l'hôpital gynéco-obstétrique et pédiatrique de Yaoundé: une analyse rétrospective sur cinq ans. Clin Mother Child Health. 2010;7(1):1201-4.

Nayama M, Gallais A, Ousmane N. Management of ectopic pregnancy in developing countries: example of a Nigerian reference maternity. Gynecol Obst Fertil. 2006;34(1):14-8

Thonneau P, Hijazi Y, Goyaux N, et al. Ectopic pregnancy in Conakry Guinea. Bull World Health Organ. 2002;80(5):365-70.

Sindayirwanya JB, Harakeye MG, Ninteretse G et al. Aspects particuliers des grossesses extra-utérines au Burundi: à propos de 249 cas. Med Afr Noire. 1991;38(5):335-41.

Majhi AK, Roy N, Karmakar KS. Ectopic pregnancy-an analysis of 180 cases. J India Med Assoc. 2007;105(6):308-12.

Kouam L, Kamdom-Moyo J. Treatment of ectopic pregnancies by laparotomy in under-equipped countries. A series of 144 cases at the Yaounde University Hospital Center (Cameroon). J Gynecol Obst et Biol Reprod (Paris). 1996;25(8):804-8.

Tumenta TS. Clinical and therapeutic aspects of ectopic pregnancy in Yaoundé. (Thèse) (2006): Faculté de Medecine et de Sciences Biomédicales de Yaoundé I.

Mohamed R. Prise en charge de la grossesse extra-utérine au service de gynéco-obstétrique B, à propos de 86 cas. (Thèse) (2006) Maroc.