DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20204843

Pregnancy in porphyria and its complications: a case report

Tuhina K. Mital, Rujuta P. Fuke

Abstract


As with many rare diseases, little is known about the porphyrias and reproduction. Knowledge pertaining to complications in pregnancy in a patient with porphyria is even more scant. The information which we have is from attending on individual cases. The following case report demonstrates a rare case of porphyria cutanea tarda in a 30 year old female patient, diagnosed around pubertal age, who presented to the Emergency department as a case of severe anemia who had delivered a still born baby the same day. Still births along with spontaneous abortions, preeclampsia and low birth weights are few of the known complications of pregnancy in patients with porphyria.


Keywords


Porphyria cutanea tarda, Acute intermittent porphyria, Stillbirth, Preeclampsia, Pregnancy

Full Text:

PDF

References


Brodie MJ, Moore MR, Thompson GG, Goldberg A, Low RA. Pregnancy and the acute porphyrias. Br J Obstet Gynaecol. 1977;84:726-31.

Aggarwal N, Bagga R, Sawhney H, Suri V, Vasishta K. Pregnancy with acute intermittent porphyria: a case report and review of literature. J Obstet Gynaecol Res. 2002;28:160-2.

Andersson C, Innala E, Backstrom T. Acute intermittent porphyria in women: clinical expression, use and experience of exogenous sex hormones. A population-based study in northern Sweden. J Intern Med. 2003;254:176-83.

Muralidhar A, Vikram RS, Pechtor K, Howells MR. Recurrent variegate porphyria in a pregnant woman. J Obstet Gynaecol. 2006;26:809-10.

Dajer A, Cooper L. Acute Intermittent Porphyria. Case Report. Emergency Medicine. 2016;48(3):123-5.

Martinez N, Anibal N, Maria G, Soraya H, Alvaro Z. Porphyria and Pregnancy. Case Report. Colomb Med. 2011;42:107-10.

Enriquez de Salamanca R. Tratamiento de las porfirias. Informacion Terapeutica del Sistema Nacional de Salud. 1990;14:198-10.

Ochaita LP. Dermatologia: texto y atlas. 3rd ed. Madrid: Editorial Pablo Lazaro Ochaita; 2003.

Gonzalez CJ, Lopez RE, Herrera ABP, Alfaro AJ, Navarro MC, Chavez SG, et al. Intermitente en el embarazo. Am Med Assoc Med Hosp ABC. 2006; 51:134-7.

TollÄnes MC, Aarsand AK, Sandberg S. Excess risk of adverse pregnancy outcomes in women with porphyria: a population-based cohort study. J Inherit Metab Dis. 2011;34(1):217-23.