DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20203330

Abnormal semen parameters among males in infertile couples: a cross sectional study from a tertiary care centre

Jyoti Garg, Rachana Meena, Shailaja Shukla, Sunita Sharma, Riva Choudhury

Abstract


Background: In India, the prevalence of primary infertility ranges from 3.9% to 16.8%. Male factor contributes 40-50% of this. Male factor infertility is indicated by decreased sperm concentration, reduced motility, vitality or abnormal sperm morphology. Semen analysis is the single most important investigation to detect male factor infertility. The aim of this study was to analyse the prevalence of abnormal semen parameters among males in infertile couples and their association with contributing factors.

Methods: This cross-sectional hospital-based study was carried out in the Department of Pathology at Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital. A total of 400 cases were analyzed during a period of 6 months. Detailed history of the couple was taken. Semen analysis was done using automated semen analyzer (SQA-vision) after 3 days of abstinence according to the WHO 5th edition 2010 guidelines. The results were analysed using excel sheet and SPSS software.

Results: In the present study, 122 cases (30.5%) out of 400 cases had abnormal semen parameters. Most common abnormality detected was asthenozoospermia (14.3%) followed by oligozoospermia (13.8%), azoospermia (10.5%) and teratozoospermia (10.5%). There was significant association of alcohol intake, obesity and trauma with abnormal semen parameters.

Conclusions: Asthenozoospermia was the most common abnormality noted in this study. Lifestyle modifications along with timely medical attention in male partners of infertile couples can improve the semen quality.


Keywords


Alcohol, Asthenozoospermia, Male infertility, Semen analysis

Full Text:

PDF

References


Sciarra J. Infertility: an international health problem. Int J Gynaecol Obstet. 1994;46:155-63.

Population Council. New Delhi: population council. infertility. Looking back, looking forward: a profile of sexual and reproductive health in India; 2004;67-72.

Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K, et al. International committee for monitoring assisted reproductive technology (ICMART) and the world health organization (WHO) revised glossary of ART terminology. Fertil Steril. 2009;92:1520-4.

Calverton, Maryland, USA: ORC Macro and the World Health Organization. World Health Organization. Infecundity, Infertility, and Childlessness in Developing Countries. DHS Comparative Reports No 9; 2004.

Men's health - male factor infertility. University of Utah Health Sciences Center. Available at: http://web.archive.org/web/20080620064743/http://healthcare.utah.edu/healthinfo/adult/men/infertil.ht. Accessed on 11th 2019.

Brugh VM, Lipshultz LI. Male factor infertility: evaluation and management. Med Clin North Am. 2004;88(2):367-85.

Hirsh A. Male subfertility. BMJ. 2003;327(7416):669-72.

Biradar KD. Male factor in infertility: study from a tertiary care hospital. Int J Reprod Contracept Obstet Gynecol. 2016;5:2022-5.

World Health Organization.WHO laboratory manual for the Examination and processing of human semen. 5th ed. Switzerland: World Health Organization; 2010: 1-102.

Bodal VK, Malik R, Kaur S, Bal MS, Kaur P, Bhagat R, Singh KD, Goel A. Seminogram in male partners of infertile couples. Int J Med Dent Sci. 2014;3(1):276-84.

Ugboaja JO, Monago EN, Obiechina NJ. Pattern of semen fluid abnormalities in male partners of infertile couples in Southeastern, Nigeria, Niger J Med. 2010;19(3):286-8.

Adenijiv RA, Olayemi O, Okunlola MA, Aimakhu CO. Pattern of Semen analysis of male partners of infertile couples at the University College Hospital, Ibadan. West Afr J Med. 2003;22(3):243-5.

Kulkarni SN, Kulkarni NV. Study of semen parameters in male partners among infertile couples. Int J Reprod Contracept Obstet Gynecol. 2015;4:1016-9.

Bhaduri N, Sarkar AP, Dewasi N, Ghosh TK. Abnormalities in semen analysis among male partners of infertile couples: a study in a tertiary care level hospital of West Bengal, India. Int J Reprod Contracept Obstet Gynecol. 2015;4:100-2.

Joshi P, Gopal N, Bhat V. Study of semen analysis patterns in infertile males. Int J Pharm Bio Sci. 2011;1(1):44-9.

Agu O, Ibrahim SA, Muhammad Z. Determination of the semen quality in male partners of infertile couples in AMINU Kano teaching hospital, Kano. Ibom Med J. 2015;8(1):194-8.

Butt F, Akram N. Semen analysis parameters: Experiences and insight into male infertility at a tertiary care hospital in Punjab. J Pak Med Assoc. 2013;63(5):558-62.

Raymont A, Arronet GH, Arrata WSM. Review of 500 cases of infertility. Fertil Family. 1970;25(2):158-61.

Kistner RW. A rational approach to theevaluation of infertility. In: Behrman SJ and Kistner RW (eds). Progress of infertility. 2nd ed. Boston: Little Brown; 1975:1-14.

Dor J, Homburg R, Rabau E. An evaluation of etiologic factors and therapy in 665 infertile couples. Fertil Steril. 1977;28(7):718-22.

Joo KJ1, Kwon YW, Myung SC, Kim TH. The effects of smoking and alcohol intake on sperm quality: light and transmission electron microscopy findings. J Int Med Res. 2012;40(6):2327-35.

Samal S, Dhadwe K, Gupta U. Epidemiological study of male infertility. Indian Med Gazette. 2012;5:174-80.

Kalyani R, Basavaraj PB, Kumar ML. Factors influencing quality of semen: a two-year prospective study. Indian J Pathol Microbiol. 2007;50(4):890-5.

Biradar KD. Male factor in infertility: study from a tertiary care hospital. Int J Reprod Contracept Obstet Gynecol. 2016;5:2022-5.