Vertical transmission of SARS-CoV-2: a brief literature review

Authors

  • Moukit Mounir Department of Obstetrics and Gynecology, Military Training Hospital Mohammed V., Rabat, Morocco
  • Assia El Ouardi Department of COVID-19, University Hospital Center Hassan II, Fes, Morocco
  • Abdellah Babahabib Department of Obstetrics and Gynecology, Military Training Hospital Mohammed V., Rabat, Morocco Department of Medicine and Pharmacy, University Mohammed V., Rabat, Morocco
  • Mehdi El Hassani Department of Obstetrics and Gynecology, Military Training Hospital Mohammed V., Rabat, Morocco Department of Medicine and Pharmacy, University Mohammed V., Rabat, Morocco
  • Jaouad Kouach Department of Obstetrics and Gynecology, Military Training Hospital Mohammed V., Rabat, Morocco Department of Medicine and Pharmacy, University Mohammed V., Rabat, Morocco

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20203355

Keywords:

Infected mother, Neonate, Pregnancy, SARS-CoV-2, Vertical transmission

Abstract

As COVID-19 virus is still spreading, more infections in pregnant women are likely to be seen. At this time, very little is known about vertical transmission of SARS-COV-2 from infected pregnant woman to her infant. Authors reviewed the risk of vertical transmission of COVID-19 by using data of published articles and official websites up to May 11, 2020. The searches revealed 16 articles (12 case reports/series and 4 retrospective studies) collectively comprising 194 infected pregnant women with COVID-19. 140 cases of neonates delivered from pregnant women with COVID-19 were collected. The SARS-COV-2 nucleic acid test, in day 2, was positive in 4 newborns. Based on limited data, there is no evidence for vertical transmission of COVID-19. Some studies suggestive of maternal-fetal transmission deserve careful evaluation before a definitive finding.

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Published

2020-07-23

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Review Articles