DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20201833

Primary breast lymphoma: a case report

Hafsa Taheri, Asma Hmila, Hanane Saadi, Ahmed Mimouni

Abstract


Primary breast lymphoma is a primary degeneration of the breast lymphoid tissue. Study aim to describe primary breast lymphoma; its clinical presentations, histological particularities and management methods. A 33 years-old patient with no medical history underwent a breast surgery. Its anatomo-pathological study, supplemented by immunohistochemistry, showed a primary breast lymphoma. The extension assessment was negative. The patient underwent chemotherapy with regression of the tumor. Breast lymphomas are rare conditions. Its clinical symptomatology is polymorphic and the imaging aspects are non-specific. It should be evoked in front of any breast tumor in order to avoid heavy breast surgery since the basic treatment is based on chemotherapy.


Keywords


Breast, Diagnosis, Lymphoma, Primary, Treatment

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References


Hugh JC, Jackson FI, Hanson J, Poppema S. Primary breast lymphoma: an immunohistologic study of 20 new cases. Cancer. 1990;66(12):2602-11.

López-Guillermo A, Colomo L, Jiménez M, Bosch F, Villamor N, Arenillas L, et al. Diffuse large B-cell lymphoma: clinical and biological characterization and outcome according to the nodal or extranodal primary origin. J Clin Oncol. 2005;23(12):2797-804.

Sashiyama H, Abe Y, Miyazawa Y, Nagashima T, Hasegawa M, Okuyama K, et al. Primary non-Hodgkin’s lymphoma of the male breast: a case report. Breast Cancer. 1999;6:55-8.

Avenia N, Sanguinetti A, Cirocchi R, Bistoni G, Trastulli S, D'Ajello F, et al. Primary breast lymphomas: a multicentric experience. World J Surg Oncol. 2010;8(1):53.

Validire P, Capovilla M, Asselain B, Kirova Y, Goudefroye R, Plancher C, et al. Primary breast non‐Hodgkin's lymphoma: a large single center study of initial characteristics, natural history, and prognostic factors. Am J Hematol. 2009;84(3):133-9.

Hakoda Y, Gotoh A, Kuriyama Y, Kusama M, Koyanagi Y, Serizawa H, et al. Breast MALT lymphoma: potential relationship between hormonal environment and female sex hormone receptor expression in lymphoma cells. Leukemia Lymphoma. 2001:1157-9.

Niitsu N, Okamoto M, Nakamine H, Hirano M. Clinicopathologic features and treatment outcome of primary breast diffuse large B-cell lymphoma. Leukemia Res. 2008;32(12):1837-41.

Sokolov T, Shimonov M, Blickstein D, Nobel M, Antebi E. Primary lymphoma of the breast: unusual presentation of breast cancer. The Eur J Surg. 2000;66(5):390-3.

Duncan VE, Reddy VV, Jhala NC, Chhieng DC, Jhala DN. Non-Hodgkin's lymphoma of the breast: a review of 18 primary and secondary cases. Ann Diagn Pathol. 2006;10(3):144-8.

Cohnen M, Saleh A, Germing U, Engelbrecht V, Mödder U. Bildgebende Diagnostik supradiaphragmaler Manifestationen extranodaler Non-Hodgkin-Lymphome. Der Radiologe. 2002;42(12):960-9.

Lyou CY, Yang SK, Choe DH, Lee BH, Kim KH. Mammographic and sonographic findings of primary breast lymphoma. Clin Imag. 2007;1(4):234-8.

Talwalkar S, Miranda RN, Valbuena JR, Routbort MJ, Martin AW, Medeiros LJ. Lymphomas involving the breast: a study of 106 cases comparing localized and disseminated neoplasms. Am J Surg Pathol. 2008;32(9):1299-309.

Yoshida S, Nakamura N, Sasaki Y, Yoshida S, Yasuda M, Sagara H, Abe M. Primary breast diffuse large B-cell lymphoma shows a non-germinal center B-cell phenotype. Modern Pathol. 2005;18(3):398.

Ryan G, Martinelli G, Kuper-Hommel M, Tsang R, Pruneri G, Yuen K, et aql. Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Study Group. Ann Oncol. 2007;19(2):233-41.

Coiffier B, Lepage E, Brière J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Eng J Med. 2002;346(4):235-42.

Ribrag V, Bibeau F, El Weshi A, Frayfer J, Fadel C, Cebotaru C, et al. Primary breast lymphoma: a report of 20 cases. Br J Haematol. 2001;115(2):253-6.

Avilés A, Castañeda C, Neri N, Cleto S, Nambo MJ. Rituximab and dose dense chemotherapy in primary breast lymphoma. Haematol. 2007;92(8):1147-8.