DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20196017

Correlation of maternal age with birth weight: need to reemphasize

Suyash Goel, Roshni Abichandani

Abstract


Background: Women at both ends of the reproductive age spectrum have unique outcomes which needs to be considered. Adolescents are at increased risk for anaemia, preterm delivery, fetal growth restriction and preeclampsia. The maternal mortality rate is higher on extremes of the age. However, there is marked variability of the birth wt even with in the age group from 19-35 years of age. The present study was conducted with an objective to assess the correlation of Maternal age with birth weight.

Methods: A total of 135 women between age 19-35 years were considered who had delivered at term (n=135) and women with any risk factors were excluded. Women were divided in three groups with age <25 years, 26-30 years and >30 years. Both primigravida and multigravida women were included without considering the mode of delivery.

Results: According to birth weight, 113 cases had their birth weight >2.5 kg and out of them 43, 56 and 14 cases belonged to age group <25, 26-30 and >30 years respectively while only 22 cases had their birth weight <2.5 kg and out of them 9, 8 and 5 cases had their age group <25, 26-30 and >30 years. Mean birth weight in age group <25 years was 2.96±0.46 kg, in age group 26-30 years, it was 3.19±0.47 kg and in age group >30 years it was 2.79±0.54. On applying ANOVA test, the difference was found statistically significant (p<0.01).

Conclusions: The variation in birth weight with respect to maternal age is significant. Limitation of this study was group comprising of 135 women.


Keywords


Adolescent age, Insulin like growth factor, Low birth weight, Maternal age, Pre-eclampsia, Preterm delivery

Full Text:

PDF

References


Luo ZC, Nuyt AM, Delvin E, Audibert F, Girard I, Shatenstein B, et al. Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes. J Clin Endocrinol. 2012;97(5):1720-8.

Murray PG, Clayton PE. Endocrine control of growth. Am J Med Genet Part C Semin Med Genet. 2013;163(2):76.

Forhead AJ, Fowden AL. The hungry fetus? Role of leptin as a nutritional signal before birth. J Physiol. 2009;15;587(Pt 6):1145.

Karakosta P, Chatzi L, Plana E, Margioris A, Castanas E, Kogevinas M. Leptin levels in cord blood and anthropometric measures at birth: a systematic review and meta‐analysis. Paediatr Perinat Epidemiol. 2011;25(2):150-63.

Kyriakakou M, Malamitisi-Puchner A, Militsi H. Leptin and adiponectin concentrations in intrauterine growth restricted and appropriate for gestational age fetuses, neonates and their mothers. Eur J Endocrinol. 2008;158(3):343.

Mise H, Yura S, Itoh H, Nuama MA, Takemura M, Sagawa N, et al. The relationship between maternal plasma leptin levels and fetal growth restriction. Endo J. 2007:0711120019.

Gibbs CM, Wendt A, Peters S, Hogue CJ. The impact of early age at first childbirth on maternal and infant health. Paediatr Perinat Epidemiol. 2012;26:259-84.

Kenny LC, Lavender T, McNamee R, O’Neill SM, Mills T, Khashan AS. Advanced maternal age and adverse pregnancy outcome: evidence from a large contemporary cohort. PloS One. 2013;8(2):e56583.

Pollack H, Lantz PM, Frohna JG. Maternal smoking and adverse birth outcomes among singletons and twins. Am J Public Health. 2000;90:395.

Jaddoe VW, Bakker R, Hofman A, Mackenbach JP, Moll HA, Steegers EA, et al. Moderate alcohol consumption during pregnancy and the risk of low birth weight and preterm birth. The generation R study. Ann Epidemiol. 2007;17:834-40.

Blumenshine P, Egerter S, Barclay CJ, Cubbin C, Braveman PA. Socioeconomic disparities in adverse birth outcomes: a systematic review. Am J Prev Med. 2010;39:263-72.

East PL, Felice ME. Adolescent pregnancy and parenting: findings from a racially diverse sample. Psychology: 2014:In Press.