AmnioQuick® Duo+ for diagnosis of premature fetal membranes rupture

Authors

  • M. Lutfi AbuFaza Department of Obstetrics and Gynaecology, Ahmadi Hospital, Kuwait
  • Ibrahim A. Abdelazim Department of Obstetrics and Gynaecology, Ahmadi Hospital, Kuwait Department of Obstetrics and Gynaecology, Ain Shams University, Egypt
  • Mohammed M. Al-Sherbeeny Department of Obstetrics and Gynaecology, Ain Shams University, Egypt
  • Mohamed E. M. Ibrahim Department of Obstetrics and Gynaecology, Ain Shams University, Egypt
  • Noha H. Rabei Department of Obstetrics and Gynaecology, Ain Shams University, Egypt
  • Sreelatha R. Nair Department of Obstetrics and Gynaecology, Ahmadi Hospital, Kuwait

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20160565

Keywords:

AmnioQuick® Duo , Premature fetal membranes rupture

Abstract

Background: Failure to identify women with premature fetal membranes rupture associated with infectious morbidities. Evaluation of the accuracy of AmnioQuick® Duo+ in diagnosing premature fetal membranes rupture compared to conventional diagnostic tests was the aim of this study.

Methods: 220 pregnant women ≥37 and <39 weeks` gestation studied and classified into two groups; study group (premature fetal membranes rupture) and control group (no premature fetal membranes rupture). Participants examined by trans-abdominal ultrasound (TAS) and vaginal speculum to visualize amnion leaking and for collection of samples for fern, nitrazine and AmnioQuick® Duo+ tests on admission. A final diagnosis whether the studied women had PROM or not at the initial presentation made after delivery.

Results: Sensitivity and specificity of the AmnioQuick® Duo+ to diagnose PROM was 93.6% and 86.4%; respectively compared with 72.7% and 80.9%; respectively for fern test and 76.4% and 83.6%; respectively for nitrazine test. Positive predictive value, negative predictive value and accuracy of AmnioQuick® Duo+ to detect PROM were 87.3%, 93.1% and 90%; respectively compared with 79.2%, 74.8% and 76.8%; respectively for fern test and 82.4%, 77.97% and 80%; respectively for nitrazine test. AmnioQuick® Duo+ test had higher accuracy to detect premature fetal membranes rupture compared to conventional diagnostic tests.

Conclusions: AmnioQuick® Duo+ is accurate bedside immunoassay test, better than the individual conventional diagnostic tests and can used as complementary test to improve the management of women with women premature fetal membranes rupture.

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Published

2017-02-23

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Original Research Articles