Clinicopathological analysis of ovarian tumors: a two year retrospective study

Authors

  • Kanika Chandra Department of Obstetrics and Gynecology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India
  • Neetu Arora Department of Obstetrics and Gynecology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20193163

Keywords:

Benign, Borderline, Epithelial tumours, Germ cell tumours, Histopathology, Malignant, Mature cystic teratoma, Ovarian tumours, Serous, Sex cord stromal tumours

Abstract

Background: Ovarian tumours are a heterogeneous neoplasm with a varied clinical, morphological and histological feature. Increasing mortality rate due to ovarian cancers has been reported in recent years. Ovarian tumours in post-menopausal females have high risk of malignancy and it has a very poor outcome. The aim and objective of this study was to determine clinical and histopathological spectrum and the frequency and age distribution of various ovarian tumors.

Methods: It is a retrospective observational study of patients with ovarian tumors in the department of obstetrics and gynecology, SGRRI of Medical Health & Sciences and Hospital from January 2016 to December 2017 in a total number of 86 patients. All specimens were sent to pathology department and categorised according to WHO  hispathological classification.

Results: Out of 86 cases examined, 64 cases were benign (74.4%), 3 cases were borderline (3.4%) and 19 cases were malignant (22.2%). Majority of the ovarian tumors (73.4%) were seen in the age group of 20 to 50 years. Most commonly encountered benign ovarian tumour was serous cystadenoma (58.1%). Surface epithelial tumors were the commonest tumors (64%) followed by germ cell tumors (29%).

Conclusions: A variety of benign and malignant tumours of ovary were reported in this study. Early diagnosis and appropriate treatment of ovarian neoplasms favour the good prognosis. Most common benign tumour encountered in this study was serous cystadenoma.

References

Day NE, Krishnan E. Epidemiology of gynaecological cancers. In: Shaw RW. Textbook of gynecology. 2nd Ed. Edinburgh: Churchill Livingstone; 1997: 477-487.

Lora HE, Edyta CP, Husain AN. The Female genital tract. In: Kumar V, Abbas AK, Fausto N, Aster JC (Eds.) Robbins and Cotran's Pathologic Basis of Disease, 8th edition. Philadelphia, Saunders-Elsevier; 2010:1039-1052.

Swamy GG, Satyanarayana N. Clinicopathological analysis of ovarian tumours- a study on five years samples. Nepal Med Coll J. 2010;12(4):221-3.

Rashid S, Sarwas G, Ali A. A Clinicopathological study of ovarian cancer. Mother Child. 1998;36:17-25.

Tortolero L, Mitchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer. Obstet Gynecol Clin North Am. 1994;21(1):63-75.

Yasmin S, Yasmin A, Asif M. Clinicohistological pattern of ovarian tumours in Peshawar region. J Ayub Med Coll Abbottabad. 2008;20(4):11-3.

Juan R. Rosai and Ackerman’s surgical pathology: ovary. 9th edn. Vol 2. New Delhi: Elsevier. 2004.

Murad A. Ovulation induction and ovarian tumours: the debate continues. J Pak Med Assoc. 1998;48(11):353-6.

Piver MS. Prophylactic oophorectomy: reducing the U.S. death rate from epithelial ovarian cancer: a continuing debate. Oncologist .1996;1(5):326-30.

Kumar V, Abbas AK, Asler JC. Robbins and Cotran Pathologic Basis of Disease, 9th Ed. Elsevier Saunders, Philadelphia;2015:1023.

Fathalla MF. Incessant ovulation: a factor in ovarian neoplasia?. Lancet. 1971;2(7716):163-5.

Forae GD, Aligbe JU. A histopathological overview of ovarian lesions in Benin City, Nigeria: How common is the functional cyst? Int J Med Pub Health. 2014;4(3):265-8.

Bhattarcharya MM, Shinde SD, Purandare VN. A clinicopathological analysis of 270 ovarian tumors. J Postgrad Med. 1980;26(2):103-7.

Pachori G, Meena US, Sunaria RK, Pachori P, Jethani N, Bayla T. Histopathological study of ovarian tumors in Ajmer region. Int J Med Sci Pub Health. 2016;5(7):1400-3.

Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10- year study in a tertiary hospital of eastern India. J Can Res Ther. 2011;7(4):433-7.

Gupta SC, Singh PA, Mehrotra TN, Agarwal R. A clinic pathological study of ovarian tumours. Indian J Pathol Microbiol. 1986;29(4):354-62.

Badge SA, Gosavi AV, Sulhyan KR. Histopathological study of ovarian tumors. Indian Med Gazette. 2013;345-51.

Sharma I, Sarma U, Dutta UC. Pathology of ovarian tumours: a hospital based study. Int J Med Sci Clin Invention. 2014;1(6):284-6.

Mankar DV, Jain GH. Histopathological Profile of Ovarian tumours: A twelve year institutional experience. Muller J Med Sci Res. 2015;6(2):107-11.

Prabhakar BR, Kalyani M. Ovarian tumors- prevalence in Punjab. Indian J Pathol Mirobiol. 1989;32(4):276-81.

Misra RK, Sharma SP, Gupta U, Gaur R, Misra SD. Pattern of ovarian neoplasms in eastern UP. J Obstet Gynecol. 1990;41(2):242-6.

Couto F, Nadkarni NS, Rebello MJ. Ovarian tumours in Goa: a clinic pathological study of ovarian tumours. J Obstet Gynaecol India. 1993;43(3):408-12.

Kar T, Kar A, Mohapatra PC. Intra-operative cytology of ovarian tumors. J Obstet Gynecol India. 2005;55(4):345-9.

Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J. 2008;10(2):81.

Singh S, Saxena V, Khatri SL, Gupta S, Garewal J, Dubey K, et al. Histopathological evaluation of ovarian tumors. Imp J Interdisciplinary Res. 2016;2(4):435-9.

Kuladeepa AVK, Muddegowda PH, Lingegowda JB, Doddikoppad MM, Basavaraja PK, Hiremath SS, et al. Histomorphological study of 134 primary ovarian tumors. Adv Lab Med Int. 2011;1(4):69-82.

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Published

2019-07-26

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Original Research Articles