DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20185289

Compare the efficiency of colposcopic VIA, VILI, LIQUIPREP TM and conventional Pap smear; as screening procedure for carcinoma cervix

Nithya Subbaiyan, Sabari Kasinathan

Abstract


Background: Cancer of the cervix is a leading cause of morbidity and mortality among women worldwide. Therefore, to curb the disease, there is a need to develop a screening test that has good sensitivity and specificity. The aim is to compare the efficiency of Colposcopic Via, Vili, Liquiprep TM and conventional pap smear; as screening procedure for carcinoma cervix.

Methods: This study was conducted in 100 women in the reproductive age. The pap smear and VIA are done in these cases. In positive cases, cervical biopsy and histopathological studies are done, the sensitivity and specificity of each test are determined and compared.

Results: In this study, more cases belonged to 30 - 45 years age group. Among 100 women, 15% cases had high-grade lesion. Among high-grade lesions group, one case that is 6.7% had CIN 1, 73.3% had CIN2/3 and 3cases i.e., 20% had cervicitis. Among 100 women, 1% had ASCUS result, 10% belongs to HSIL group, 39% belongs to LSIL group and 2% had an unsatisfactory result.

Conclusions: The lack of an effective and implementable screening programme lead to reporting of advanced cases of Ca Cervix. If detected at CIN or early Ca cervix stage, effective treatment can be provided with encouraging results. Therefore, effective and implementable Ca Cervix screening need to be provided in our country.


Keywords


Ca cervix, Pap Smear, VIA

Full Text:

PDF

References


Adadevoh SW, Forkoh BK, Cervical cancer Screening. Int J Gynaecol Obstet.1993;43(1):63-4

Basu P.S, Sankaranarayanan. R, Mandal. R, Roy. C, Das. P, Visual Inspection of Cervix with acetic add and cytology in the early detection of cervical neoplasia in Kolkotta - India. Int J Cancer. 2005;13(6):626-32.

Benedict JL, Matistic JP, Bertrand MA, An analysis of 84244 patients from theBritish Columbia Cytology-colposcopy program. J Gynecol 2004; 92(1):127-34.

McGraw SL, Ferrante JM. Update on prevention and screening of cervical cancer. World J Clin Oncol. 2014;5(4):744-52.

Juneja A, Murthy NS, Sharma S, Shukla DK, Roy M, Das DK. Selective cervical cytology screening: Discriminant analysis approach. Neoplasia. 1993;40(6):401-4.

Sherwani RK, Khan T. Conventional pap smear and liquid based cytology for cervical cancer screeing. J Cytol. 2007;2(4):167-72.

Kushtagi P, Fernandez P, Significance of Persistent Inflammatory, Cervical smears in Sexually active women of reproductive age. J Obstet Gynecol lndia. 2002;52(1)124 - 6.

Olaniyan OB. Validity of colposcopy in the diagnosis of early cervical neoplasia a review. African J Reproduct Health. 2002,6(3):59-69.

Shalini. R, Amita. S, Neera. M.A, How alarming is post coital bleeding – a cytologic, colposcopic and histological evaluation Gynaecol Obstet Invest. 1998;45(3):205 - 8.

Pimple SA, Amin G, Goswani S, Shastri SS. Evaluation of colposcopy vs cytology as secondary test to triage women found positive on visual inspection test. Indian J Cancer. 2010;47(2):308-13.

Divya H, Harish S, Prasanna KS, Supriya R. Diagnostic value of acetic acid comparing with conventional Pap smear in the detection of colposcopic biopsy-proved CIN. J Cancer Res Therapeut. 2011;7(4):454-8.

Donald A, Thomas T, Jaffery T, Ian S. Should liquid based cytology be performed prior to colposcopy? A comparison of the accuracy, unsatisfactory rates and cost in a referral setting. Aust NZ J Obstet Gynaecol. 2009;49(6):681-4.