DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20185402

Prevalence of blighted ovum in first trimester of pregnancy: a hospital based study

Abo Bakr A. Mitwally, Diaa Eldeen M. Abd El Aal, Nermeen Taher, Ahmed M. Abbas

Abstract


Background: The aim of this study is to know the prevalence of blighted ovum among pregnant women in 1st trimester attending our hospital during their antenatal visits and to know the fate of blighted ovum either if there is spontaneous expulsion of the sac or need of medical induction or surgical evacuation.

Methods: This observational study was conducted at Obstetrics and Genecology Department, Women Health Hospital and Sahel Selim Hospital, Egypt from November 2015 to February 2018. All patients recruited in this study attended the antenatal care clinics for antenatal follow-up during their first-trimester of pregnancies.

Results: All cases of the study were less than 14 weeks. The mean gestational age was 8.93±1.01 (7.0-11.0) weeks. In patients less than 20 years old, (73%) there is a significant increase in surgical treatment (dilatation & curettage) after failure of medical treatment, patients more than 40 years old (50.7%) there is a significant increase in medical treatment after success taking misoprostol so there is no need to a surgical treatment by (dilatation & curettage) in the majority of cases.

Conclusions: The prevalence of blighted ovum was 15.6%. Also, the prevalence of blighted ovum was statistically significant increased with increase maternal age and also, we noticed that there was a statistically significant association between early pregnancy failure and a history of previous early pregnancy loss.


Keywords


Abortion, Blighted ovum, Expulsion, Miscarriage

Full Text:

PDF

References


Regan L, Rai R. Epidemiology and the medical causes of miscarriage. Best Pract Res Clinic Obstet Gynaecol.2000;14(5):839-54.

Wang X, Chen C, Wang L, Chen D, Guang W, French J, Reproductive Health Study Group. Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study. Fertil Steril. 2003;79(3):577-84.

Petrozza JC, Berin I, Cowan BD, Smith CV, Gaup FB. Recurrent early pregnancy loss.E medicine. Arch Androl. 2012;49(1):49-55.

Wyatt PR, Owolabi T, Meier C, Huang T. Age-specific risk of fetal loss observed in a second trimester serum screening population. Am J Obstet Gynecol. 2005;192(1):240-6.

Jauniaux E, Farquharson RG, Exalto N. Updated and revised nomenclature for description of early pregnancy events. Human Reproduct. 2005;20(11):3008-11.

Portentoso A. Ercoli MG, Sartor A, Rossi G ; "Cytogenic finding in echographicallyde fined abortion." Ann. Genet. 2008.

Luise C, Jermy K, May C, Costello G, Collins WP, Bourne TH. Outcome of expectant management of spontaneous first trimester miscarriage: observational study. BMJ. 2012;324(7342):873-5

Churchill K, Simpson Jl, Jauniau X, Minelli E, Buchi P, Granata E et al Cytogenic finding in echographically defined abortion Arch Androl. 2007;49(1):49-55

Patricia LJ. A Pediatrician Looks at Babies Late in Pregnancy and Late Term Abortion. Presbyterians Pro-Life. 2001.

DeCherney F, Alan H: Current Obstetric & Gynecologic Diagnosis & Treatment – Ninth Ed ch 14, 2011.

Chaudhry K. Blighted Ovum (Anembryonic Pregnancy). In Stat Pearls 2018. StatPearls Publishing.

Pandya PP, Snijders RJ, Psara N, Hilbert L, Nicolaides KH. The prevalence of nonviable pregnancy at 10–13 weeks of gestation. Ultrasound in Obstetrics and Gynecology: The Off J Int Soc Ultras Obstet Gynecol. 1996;7(3):170-3.

Regan J, Rossal LP, Bosch E, Zúñiga A, Corona JT, Meléndez F, Gómez E, Simón C, Remohı́ J, Pellicer A. Obesity and the risk of spontaneous abortion after oocyte donation. Fertil Steril. 2003;79(5):1136-40.

Shekoohi S, Mojarrad M, Raoofian R, Ahmadzadeh S, Mirzaie S, Hassanzadeh-Nazarabadi M. Chromosomal study of couples with the history of recurrent spontaneous abortions with diagnosed blightded ovum. Int J Molecul Cell Med. 2013;2(4):164.

Turner MJ, Flannelly GM, Wingfield M, Rasmussen MJ, Ryan R, Cullen S, Maguire R, Stronge JM. The miscarriage clinic: an audit of the first year. Int J Obstet Gynaecol. 2009;98(3):306-8.

Balen AH, Anderson RA, Policy and Practice Committee of the BFS. Impact of obesity on female reproductive health: British fertility society, policy and practice guidelines. Human Fertility. 2007;10(4):195-206.

Jurkovic D, Ross JA, Nicolaides KH. Expectant management of missed miscarriage. BJOG: Int J Obstet Gynaecol. 2004;105(6):670-1.