A hydatidiform mole in a postmenopausal woman

Authors

  • Mohana Dhanapal Department of Obstetrics and Gynaecology, GMKMCH, Salem, Tamil Nadu, India
  • . Padmapriya Department of Obstetrics and Gynaecology, GMKMCH, Salem, Tamil Nadu, India
  • Anbarasi Pandian Department of Obstetrics and Gynaecology, GMKMCH, Salem, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20182376

Keywords:

Postmenopausal women, Pregnancy, Beta HCG, Hydatidiform mole

Abstract

Gestational trophoblastic disease occurs in less than 1 per 1200 pregnancies. The spectrum of this disease ranges from benign hydatidiform mole to trophoblastic malignancy (placental-site trophoblastic tumor and choriocarcinoma). Benign gestational trophoblastic disease generally occurs in women of reproductive age and is extremely rare in postmenopausal women. We report a case of a 54-year-old postmenopausal woman who underwent an emergency total abdominal hysterectomy due to uncontrollable vaginal bleeding associated with an increased serum β-human chorionic gonadotropin level. The resected uterus contained an endometrial, cystic, grapelike tumor. Microscopic examination demonstrated hydropic degenerated villi with a circumferential trophoblastic cell proliferation and moderate atypia, consistent with a complete hydatidiform mole. Only isolated cases of hydatiform mole in elderly women have been reported in literature. But there still remains a risk of developing gestational trophoblastic disease in the elderly and it should always be included in the differential diagnosis of postmenopausal bleed.

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Published

2018-05-26

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Section

Case Reports