Published: 2016-12-15

Severe anemia and adverse pregnancy outcome

Chandrika S.


Background: Anaemia is commonest medical disorder in pregnancy with 88% prevalence in India mainly due to ignorance, poverty and gender bias 40-60% of maternal deaths in developing countries. The aim of the study was to determine the association between severe anemia, maternal and perinatal complications.

Methods: Case control study was done in department of obstetrics and gynecology, Government Medical College Nagpur, India from September 2011 to February 2012. 50 pregnant women, admitted for delivery and having severe anemia were studied and compared with 100 non anemic women of similar demographic features. Maternal and perinatal complications were observed. Pearson, chi-square and Fischer exact tests were used to calculate significance of results. 

Results: Of the severely anemic mothers, 36% babies were low birth weight (p=0.042) and 20% were small for gestational age (p = 0.026), as compared to 18% and 10% of controls, respectively.

Conclusions: Severe maternal anemia carries significant risk of hemorrhage and infection in the mother. It is also associated with preterm birth, low birth weight.


Severe anemia, Hemorrhage, Preterm birth, Low birth weight

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World Health Organization. WHO Global Database. Geneva: WHO, 1997.

Sarin AR. Severe anemia in pregnancy, recent experience. Int J Gynecology Obstetric. 1995;50:45-9.

Brabin L, Nicholas S, Gogate A, Karande A. A high prevalence of anemia among women in Mumbai, India. Food Nutr Bull. 1998;19:205-9.

Marhatta R. Study of anemia in pregnancy and its outcome in Nepal Medical College Teaching Hospital, Kathmandu, Nepal. Nepal Med Coll J. 2007;9:270-4.

Gregory P, Taslim A. Health status of Pakistani population: a health profile and comparison with the United States. Am J Public Health. 2001;91:93-8.

Bhatt R. Maternal mortality in India-FOGSI-WHO Study. J Obstet Gynecol Ind. 1997;47:207-14.

Ali AA, Dam I. Anaemia and stillbirth in Kassala hospital, eastern Sudan. J Trop Pediatr. 2011;57(1):62-4.

Karaflahin E, Ceyhan ST, Goktolga U, Keskin U, Bafler S. Maternal anemia and perinatal outcome. Perinatal J. 2007;15(3):129.

Kavle JA. Maternal anemia and blood loss at child birth and postpartum in Zanzibar, Tanzania. Baltimore, MD: Bloomberg School of Public Health, Johns Hopkins University, 2005:204.