Published: 2016-12-15

Correlations of adherence to iron supplements and prevalence of anemia in antenatal women

Manjusha Sajith, Vandana Nimbargi, Sejal Shah, Srushti Tekawade, Jayesh Agiwale, Atmaram Pawar


Background: The prevalence of anemia in pregnant women has remained unacceptably high worldwide despite the fact that routine iron supplementation during pregnancy has been almost universally recommended to prevent maternal anemia. The major problem with iron supplementation during pregnancy is compliance. The objective of this study was to correlate iron supplements compliance among pregnant women and incidence of anemia during pregnancy.

Methods: A Prospective observational study was conducted over a period of nine months from August 2015 to April 2016 in the department of obstetrics and gynecology, Bharati Hospital and Research Center, Pune. Pregnant women more than 14 weeks who attended antenatal care unit were enrolled in this study. Data for compliance was collected by two methods - first by personal interview as well as looking for the empty iron tablet strips. Pregnant women were followed till the date of delivery and maternal outcome were noted.

Results: Our results show that 64% were strictly compliant, 33% with partially complaint and 3% with non-complaint with iron supplements. The mean Hemoglobin concentration of pregnant women who strictly complies with iron supplements were 11.6 g/dl where the non-compliant and partially complaint to iron supplements were 9.7 g/dl. The prevalence of anemia was found to be more in partial and non-compliant to iron supplements (13% p value <0.001).

Conclusions: Anaemia, low haemoglobin levels were found more in non-complaint and partially complaint pregnant women. The findings from our study highlighted that antenatal health and a nutritional intervention program for pregnant women is needful.


Pregnancy Outcome, Knowledge, Awareness, Compliance of iron supplementation

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Bothwell TH. Iron requirements in pregnancy and strategies to meet them. Am J Clin Nutr. 2000;72(suppl):257S-64S.

Habib F, Alabdin EH, Alenazy M, Nooh R. Compliance to iron supplementation during pregnancy. J Obst Gyne. 2009;29(6):487-92.

Ladipo OA. Nutrition in pregnancy: mineral and vitamin supplements. Am J Clin Nutr. 2000;72(suppl):280S-90S.

Bhandare B, Kauser SV, Safina. Prescribing pattern of iron preparations in antenatal women in a tertiary care hospital. J Int Med Dent. 2014;1(1):23-7.

Ahmed EB, Ali EA, Mohamed EH, Saleh EA, Abd Elbaset AK, Mahmmed EM, et al. Assessment of iron and calcium supplements compliance among pregnant women attending antenatal care unit” of Alsabah Banat primary health care unit in Ismailia, Egypt. J Med Bio Sci Res. 2015;1(3):24-9.

Ugwu EO, Olibe AO, Obi SN, Ugwu AO. Determinants of compliance to iron supplementation among pregnant women in Enugu, Southeastern Nigeria. Niger J Clin Pract. 2014;17(5):608-12.

Thirukkanesh S, Zahara AM. Compliance to vitamins and mineral supplementation among pregnant women in urban and rural areas in Malaysia. Pak J Nutr. 2010;9(8):744-50.

Benali AI, Demmouche A. Calcium deficiency among pregnant women and their newborns in Sidi Bel Abbes Region Algeria. J Nutr Food Sci. 2014;4:318.

Daba G, Beyene F, Fekadu H, Garoma W. Assessment of knowledge of pregnant mothers on maternal nutrition and associated factors. In Guto Gida Woreda, East Wollega Zone, Ethiopia. J Nutr Food Sci. 2013;3:235.