The use of misoprostol in outpatient treatment of abortions in the first quarter of pregnancy in Dakar

Authors

  • M. M. Niang Department of Obstetrics and Gynecology, Cheikh Anta Diop Univesity of Dakar, Social Hygiene Institute Hospital, Dakar, Senegal
  • N. A. Fall Augowet Department of Obstetrics and Gynecology, Aristide Le Dantec Hospital, Senegal
  • D. Diallo Department of Obstetrics and Gynecology, Cheikh Anta Diop Univesity of Dakar, Social Hygiene Institute Hospital, Dakar, Senegal
  • M. Thiam Department of Obstetrics and Gynecology, Univesity of Thies, Senegal
  • J. C. Moreau Department of Obstetrics and Gynecology, Cheikh Anta Diop Univesity of Dakar, Aristide Le Dantec Hospital
  • C. T. Cisse Department of Obstetrics and Gynecology, Cheikh Anta Diop Univesity of Dakar, Social Hygiene Institute Hospital, Dakar, Senegal

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20174987

Keywords:

MVA, Miscarriages, Misoprostol

Abstract

Background: The objective of this study was to compare the effectiveness of misoprostol comparing to MVA in support of abortion from the first quarter.

Methods: This was a prospective, descriptive and analytical study (case-control study) made between January 1st and December 31st, 2015 in a level 1 maternity in Dakar.

Results: The study included316 first trimester abortions (158 were treated with misoprostol and 158 with MVA). The epidemiological profile was a woman aged on average 28.5 years and nulliparous (37%). The mean gestational age was 8 weeks 6 days. The rate of complete uterine evacuation was comparable in both groups (93% for misoprostol versus 94.3%for MVA) with a non-significant p-value. Side effects found (40.8%) were minor. The hospital stay averaged two hours in the misoprostol group against 24 hours for MVA. Anaemia was more common in the MVA group (44.1%) than in the misoprostol group (23.6%) (p = 0.0006). The cost of treatment with misoprostol (5620 CFA francs) was on average four times less than that of MVA (21,623 CFA francs).

Conclusions: Misoprostol can be seen as a credible alternative in the management of first quarter abortions because of its many advantages including its effectiveness, its easiness to be used in ambulatory, its low cost and safety.

References

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Published

2017-10-28

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Original Research Articles