DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20190903

Comparative study of causative organism in erosive cervicitis, cervical intra epithelial neoplasia and carcinoma cervix using Pap smear

Jyoti Bindal, Deepak Paldiya

Abstract


Background: Cervical cancer is the third largest cause of cancer mortality in India after cancers of the mouth and oropharynx, and oesophagus, accounting for nearly 10% of all cancer related deaths in the country.

Methods: The present study carried out 300 patients in Gajra Raja Medical College in the Department of Obstetrics and Gynaecology, OPD and indoor admitted patients from July 2016 to December. 2016. The selected patients were examined with care to note any cervical lesion, appearance of cervix, nature of any cervical/ vaginal discharge. Then a cervical scrape was taken with an Ayre’s spatula and slide stained and then examined.

Results: The maximum cases of HPV were seen in CIN, LSIL and HSIL. Maximum incidence of all cases was seen in the age group of 30-50 yrs. The women married before 18 years had the highest incidence of CIN and HPV infection. Majority of the cases of cervicitis were co-infected with H-Vaginalis and Trichomonas. Most women opted for a sterilization procedure rather than any other method of contraception. Use of no contraception puts these women at a high risk of acquiring HPV infection from infected partners.

Conclusions: Occurrence of HPV infection declines with increasing grades. Most of the patients with HPV infection had presented with non-specific symptoms of discharge P/V or lower abdominal pain.


Keywords


Cervical cancer, CIN, HPV infection

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References


Parimala A, Sharma N, Srinivasan JK. Screening of cancer cervix: Paper smear in rural India. Int J Reprod Contracept Obstet Gynecol. 2016;5(7):2113-5.

Bal MS, Goyal R, Suri AK, Mohi MK. Detection of abnormal cervical cytology in Papanicolaou smears. J Cytol. 2012;29(1):45-7.

American College of Obstetricians and Gynaecolgists. Cervical cancer screening and prevention. Practice Bulletin No. 157. Obstet Gynecol. 2016;127(1):1-20.

Gibb RK, Martens MG. The impact of liquid based cytology in decreasing the incidence of cervical cancer. Rev Obstet Gynecol. 2011;4(1):S2-11.

Saraiya U, Gupta PC, Lulla M, Garud M. Formulation of a scoring system based on disicriminant analysis of risk factors in development of cervical cancer-a comparative study of cases of cancer, dysplasia and control group. 26th Conference of Federation of Obstetrics and Gynaecology Societies of India; 1983:508-511.

Parkin DM. The global health burden of infection‐associated cancers in the year 2002. Int J Cancer. 2006;118(12):3030-44.

Mohanty J, Mohanty BK. J Obstet Gynecol India.1991;41(3):403-6.

Africa SS. Long term pill use, high parity raise cervical cancer risk among women with human papillomavirus infection. International Perspective on sexual and reproductive health. A J Peer-reviewed Res 2002;28(3):176-177.

Paba P, Bonifacio D, Di Bonito L, Ombres D, Favalli C, Syrjanen K, et al. Co-expression of HSV2 and Chlamydia trachomatis in HPV-positive cervical cancer and cervical intraepithelial neoplasia lesions is associated with aberrations in key intracellular pathways. Intervirol. 2008;51(4):230-4.

Kone ES, Balilli AD, Paparisto PD, Ceka XR, Petrela ED. Vaginal infection of Albanian women infected with HPV and their impact in intraepithelial cervical lesions evidenced by Pap test. J Cytol 2017;34(1):16-21.