Periodontitis as a risk factor for preterm labour and low birth weight among pregnant women attending a tertiary care teaching hospital

Authors

  • Saranya Chokkaiyan Department of Obstetrics and Gynecology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
  • Sendhil Coumary Arumugam Department of Obstetrics and Gynecology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
  • Saravana Kumar Department of Periodontology, Indira Gandhi Institute of dental Sciences, Puducherry, India
  • Lopa B John Department of Obstetrics and Gynecology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
  • Seetesh Ghose Department of Obstetrics and Gynecology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20151264

Keywords:

Periodontitis, Preterm labour, Low birth weight, Case-control study

Abstract

Background: Preterm birth is the single most important factor affecting perinatal outcome in terms of both morbidity and mortality. Chronic infections in mother are being implicated as a cause of preterm labour. The objective of this study was to find out a causal association between periodontitis and preterm labour or low birth weight. It was a Case- Control Study. This study was conducted in Mahatma Gandhi Medical College and Research Institute, Puducherry between February 2013 and June 2014.

Methods: A total of 200 women were included in the study with 100 women in each group (cases and controls). Cases included women who had spontaneous preterm labour or threatened PTL (gestational age 28- 36 weeks) or women who had delivered a baby with the birth weight being less than 2.5 kg. Controls were patients who had a normal labour with the gestational age of more than 37 weeks with birth weight of the baby more than 2.5 kg. Periodontal examination was done for both cases and controls. Periodontal factors like Plaque Index (PI), bleeding Index (SBI), Probing pocket depth (PD) and Clinical attachment level (CAL) were examined for both groups. Student t test, Chi-square and Fisher Exact has been used for statistical analysis.

Results: In the present study, plaque index and bleeding index was significantly more in cases than controls with a p value of 0.009 and 0.035 respectively. Evidence of periodontitis was seen in 86% of cases and 76% of controls respectively which was also statistically significant with a p value of 0.071.Moderate periodontitis was found in significant number cases and was statistically significant with a P value of <0.001.

Conclusions: This suggests that there exists an association between moderate periodontitis and preterm labour and low birth weight.

References

WHO fact sheet N*363 updated November 2014

Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics. 23rd ed. United States of America: McGraw-Hill Companies; 2010;804-27.

Paquette DW. The periodontal infection-systemic disease link: a review of the truth or myth. J Int Acad Periodontol 2002;4:101.19.

Damare SM, Wells S, Offenbacher S. Eicosanoids in periodontal diseases: potential for systemic involvement. Adv Exp Med Biol. 1997;123:23-35.

Offenbacher S. Periodontal diseases: pathogenesis. Ann Periodontol. 1996;11:821-78.

López NJ, Da Silva I, Ipinza J, Gutiérrez J. Periodontal therapy reduces the rate of preterm low birth weight in women with pregnancy associated gingivitis. J Periodontol. 2005;76(11 Suppl):2114-53.

Gundala R, Chava VK. Effect of lifestyle, education and socioeconomic status on periodontal health. Contemp Clin Dent. 2010;11:23–6.

Mannem S, Chava VK. The relationship between maternal periodontitis andpreterm low birth weight: A Case-Control Study. Contemp Clin Dent. 2011;2(2):88-93.

Jacob PS, Nath S. Periodontitis among poor rural Indian mothers increases the risk of low birth weight babies: a hospital-based case control study. J Periodontal Implant Sci. 2014;44(2):85-93.

Gandhimadhi and Mythili R. Periodontal infection as a risk factor for pretermlow birth weight. J Indian soc periodontol. 2010;14(2):114-20.

Alves RT, Ribeiro RA. Relationship between maternal periodontal disease and birth of preterm low birth weight babies. Braz Oral Res. 2006;20(4):318-23.

Wang YL, Liou JD, Pan WL. Association between maternal periodontal disease and preterm delivery and low birth weight. Taiwanese Journal of Obstetrics & Gynecology. 2013;521:71-6.

Nabet C, Lelong N, Colombier ML, Sixou M, Musset AM, Goffinet F, et al. Epipap Group. Maternal periodontitis and the causes of preterm birth: the case-control Epipap study. J Clin Periodontol. 2010;371:37-45.

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Published

2017-02-19

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Original Research Articles