Selected risk factors of infertility in women: case control study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20151129Keywords:
Infertility, Risk factors, WomenAbstract
Background: Infertility implies apparent failure of a couple to conceive. If a couple fails to achieve pregnancy after one year of unprotected intercourse, it is an indication to investigate the couple. This is based on the observation that, 80% of the normal couples achieve conception within a year.
Methods: A case control study on the selected risk factors of female infertility among fifty females attending the Tertiary care centre was conducted. The data was collected from fifty cases and fifty controls, matched for age, using a pre-structured questionnaire. The data collected included menstrual details, uterine or ovarian disorders, genito-urinary infections, systemic illness, hyperprolactinemia and weight gain. Data was analysed to find out risk factors and its association using Odds ratio, chi-square and logistic regression.
Results: The factors include age, duration of menstrual cycles, dysmenorrhea, Hyperprolactinemia, recent weight gain, body mass index (BMI), ovarian dysfunctions, thyroid disorders and uterine abnormalities.
Conclusions: Early screening and diagnosis of menstrual disorders and diseases like hyperprolactinemia, Thyroid disorders, uterine abnormalities, ovarian dysfunctions and correcting them by appropriate treatment.
References
World Health Organization. Female infertility. Techn Report series. 1998:401.
Frank O. Worldwide infertility: Estimation and implications. Population development review. 1993;9:137-44.
Dutta DC. Textbook of Gynaecology. 5 th Edition. 2009:220.
Sharath KC, Najafi M, Malini SS. Association of Obesity with Male Infertility among Infertile Couples is not Significant in Mysore, South India. Advanced Studies in Biology. 2013;5:319-25.
Buckett B, Bentick B. The epidemiology of infertility in a rural population. Acta Obstet Gynecol Scand. 1997;76:233-7.
Booth M, Beral V. Treatment of PCOS. J Middle East Fertil Soc. 2000;5:120-5.
Ralph S, Rutherford A, Wilson J. Influence of bacterial vaginosis on conception and miscarriage among infertile women. BMJ. 1999;319:220-3.
Cornillie F, Oosterlynck D, Lauweryns J, Koninckx p. Population study of causes and risk factors of infertility. BMJ. 1995;291:1693-7.
David L. Alcohol reduces fertilization success. Lancet. 1994;18:276-9.
William B. Population study of the epidemiology of infertility. Acta Obstet Gynecol Scand. 1997;76:233-7.
Regan L, Owen E, Jacobs H. Surgery and risk of infertility and miscarriages. Lancet. 1990;336:1141-4.
Giwercman A, Kretser D, Skakkebaek N. Risk factors of infertility. Lancet. 1994;343:1473-9.
Kennedy H. Infertility in women of advanced reproductive age. Am J Obst Gynecol. 1999;181:952-7.
Mc Donald J, Mc Quinn B, Mc Clure N. Anovulatory polycystic ovarian syndrome. Fertil Steril. 1993;59:729-33.
Franks S. Polycystic Ovary Syndrome. N Engl J Med 1995;333:853-61.