Neurofibromatosis in pregnancy: study of 2 cases

Authors

  • Khushboo Jain Department of Obstetrics & Gynaecology, Government Medical College, Kota, Rajasthan, India
  • Mamta Sharma Department of Obstetrics & Gynaecology, Government Medical College, Kota, Rajasthan, India
  • Hitesh Mangal Department of Orthopaedics, Government Medical College, Kota, Rajasthan, India

Keywords:

Pregnancy, Neurofibromatosis, Placenta praevia

Abstract

The report presents two cases of neurofibromatosis (NF) and illustrates how women with NF have increased complications associated with pregnancy. With these case reports, we wanted to describe the diagnostic possibilities, management of pregnancies and dilemmas in everyday clinical practice of a gynaecologist.

References

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Origone P, Bonioli E, Panucci E, Costabel S, Ajmar F,Coviello DA. The Genoa experience of prenatal diagnosis in NF1. Prenatal Diagnosis. 2000;20(9):719-24.

Posma E, Aalbers R, Kurniawan YS, van Essen AJ, Peeters PM, van Loon AJ. Neurofibromatosis type I and pregnancy: a fatal attraction? Development of malignant schwannoma during pregnancy in a patient with neurofibromatosis type I. BJOG. 2003;110(5):530-2.

Isikoglu M, Has R, Korkmaz D,Bebek N. Plexiform neurofibroma during and after pregnancy. Arch Gynecol Obstet. 2002;267(1):41-2.

Nebesio TD, Ming W, Chen S, Clegg T, Yuan J, Yang Y, et al. Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration—implications for increased neurofibroma formation during pregnancy. Glia. 2007;55(5):527-36.

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Published

2017-02-06

Issue

Section

Case Reports