A study on faeto-maternal outcome in pregnancy with jaundice due to hepatitis E

Authors

  • Sushanta Kumar Jena Department of Community Medicine, Shri Ramachandra Bhanj Medical College, Cuttack, Odisha, India
  • Minakshi Mohanty Department of Community Medicine, Shri Ramachandra Bhanj Medical College, Cuttack, Odisha, India
  • Sasmita Behuria Department of Obstetrics and Gynaecology, Shri Ramachandra Bhanj Medical College, Cuttack, Odisha, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20170513

Keywords:

Hepatitis E, Jaundice in pregnancy

Abstract

Background: Hepatitis E virus is a non-envelope RNA virus responsible for large epidemics in Asia, the Middle east Mexico and Africa. It spreads via the feco-oral route, and has an incubation period of 8-10 weeks. The objective of the study was to find out the effect of hepatitis E during pregnancy on faeto-maternal outcome.

Methods: A study on faeto-maternal outcome of 38 pregnant women admitted with jaundice due to hepatitis E to the Department of Hepatology, Shri Ramachandra Bhanj (SCB) Medical College, Cuttack, Odisha, India during January 2015 to December 2015.

Results: 38 Pregnant women admitted to the Department of Hepatology of SCB Medical College, Cuttack, Odisha, India were studied. 65.7% were from rural area, 92.1% were in their third trimester of pregnancy. Serum bilirubin >10 mg in 52.19 %, SGOT, SGPT and alkaline phosphatase were raised in majority of them. Out of 38 women 32 delivered and 6 remain undelivered. In 81.25% of cases labor was spontaneous, perinatal mortality was observed in 46.87% of cases and 5 women died during child birth.

Conclusions: When pregnancy is associated with jaundice due to hepatitis E, there is high perinatal and maternal morbidity and mortality. Early diagnosis and careful management is required for such cases.

References

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Published

2017-02-19

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Section

Original Research Articles