Invasive mole: a rare cause of postmenopausal bleeding

Authors

  • Mamour Guèye Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal
  • Mamadou Lamine Cissé Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal
  • Mame Diarra Ndiaye-Guèye Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal
  • Magatte Mbaye Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal
  • Serigne Modou Kane-Guèye Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal
  • Jean Charles Moreau Gynaecologic and Obstetric Clinic, Aristide Le Dantec Teaching Hospital. 1, Avenue Pasteur, POBox 3001, Dakar, Senegal

Keywords:

Post-menopausal, Invasive mole, Gestational Trophoblastic Neoplasia

Abstract

Gestational trophoblastic disease (GTD) describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial), placental site trophoblastic tumour, choriocarcinoma and invasive mole. Invasive moles are responsible of most cases of localized gestational trophoblastic neoplasia (GTN). Invasive mole is a condition where a molar pregnancy, such as a partial hydatidiform mole or complete hydatidiform mole, invades the wall of the uterus. It is an extremely rare condition. As GTN is not considered in the differential diagnosis of postmenopausal uterine malignancies, its preoperative diagnosis is challenging. We report a case of invasive hydatidiform mole in a postmenopausal woman discovered in a context of postmenopausal bleeding. She underwent hysterectomy and followed up till her beta hCG levels were within normal limits. The patient is in complete remission in the first postoperative year. 

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Published

2016-12-10