Study of hypothyroidism in pregnancy and it’s fetomaternal outcome: a prospective study at tertiary care hospital

Authors

  • Monika . Department of Obstetrics and Gynecology, RNT Medical College, Udaipur, Rajasthan, India
  • Susheela Khoiwal Department of Obstetrics and Gynecology, RNT Medical College, Udaipur, Rajasthan, India
  • Aditi Mourya Department of Obstetrics and Gynecology, RNT Medical College, Udaipur, Rajasthan, India
  • Nisha Sharma Department of Obstetrics and Gynaecology, Military Hospital, Nashirabad, Rajasthan, India
  • Anju Jorwal Department of Obstetrics and Gynecology, RNT Medical College, Udaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20223130

Keywords:

Hypothyroidism and anemia, Pregnancy and hypothyroidism, Subclinical hypothyroidism, Thyroid dysfunction in pregnancy

Abstract

Background: Pregnancy is a stress test of maternal thyroid function. The prevalence of thyroid dysfunction in pregnant women is high. This study is aimed to evaluate maternal and fetal outcomes in pregnant women with deranged thyroid profile. The relevance of this study is to document the association of hypothyroidism and its adverse effects on mother and fetus.

Methods: All pregnant mother included in the study are subjected to written consent and detailed history taking and fasting blood sample collection. Blood sample collected in fasting state, because lipidemic content in blood interferes with serum thyroid stimulating hormone (TSH) level if blood sample collected in the fed state.

Results: A total of 1000 cases were studied. Out of 1000 cases, 71(7.1%) cases found to be hypothyroid. Among them, 14 (19.4%) had overt hypothyroidism and 57 (80.5%) demonstrated subclinical hypothyroidism.

Conclusions: Prevalence of subclinical hypothyroidism is 5.6% in 3rd trimester of pregnancy. Anemia, pre-eclampsia, high caesarean rates and neonatal morbidities is significantly associated with hypothyroidism.

 

References

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Published

2022-11-25

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Original Research Articles