Published: 2022-10-28

Study of maternal and perinatal outcome in case of premature rupture of membrane at term

Ridhdhi B. Rangrej, Akshay C. Shah, Babulal S. Patel, Purvi M. Parikh, Kiran M. Patel


Background: Premature rupture of membranes is characterized by the rupture of membranes before the onset of true labour. PROM is associated with a high risk of maternal morbidity and also perinatal morbidity and mortality. The objective of this study was the evaluation of various risk factors and maternal and perinatal outcomes for a better understanding of this oracular condition for its better understanding and timely management.

Methods: This study was carried out on 75 cases of PROM fulfilling set criteria over one year at a tertiary care hospital of western India. Demographic details, risk factors and outcomes were studied.

Results: Present study found the highest number of cases among the age group 21-24 years. 70% of patients were primigravida and almost 75% were un-booked. Around 2/3rd of cases were delivered vaginally, having the highest no of maternal and perinatal morbidity and mortality when the duration of PROM increased to more than 24 hours.

Conclusions: In our study, it was seen that PROM is more commonly seen in younger primigravida having certain risk factors. Many delivered vaginally. Complications increased with increasing duration of PROM. Early recognition of premature rupture of membranes and their associated complications and appropriate management of the situation helps in reducing the problems due to PROM to a great extent.


Maternal and perinatal outcome, Premature rupture of membrane, Primigravida, Vaginal delivery

Full Text:



Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, et al. Williams’ Obstetrics. 25th edn. McGraw-Hill; 2018, p. 447.

Umed T, Aitra N, Baxi S, Hazra M. Labor characteristics in pre-labor rupture of membranes. J Obstet Gynecol India. 1994;44:527.

Duff P. Premature rupture of membranes in term patients: induction of labor versus expectant management. Clin Obstet Gynecol. 1998;41:883-91.

Jayaram VK, Sudha S. A study of PROM-management, and outcome. J Obstet Gynecol India. 2001;51:58-60.

Jiwane KA. Antenatal vaginal examination as a cause of PROM. J Obstet Gynecol India. 1991;41:337.

Kodkany BS, Telang MA. Premature rupture of membranes. A study of 100 cases. J. Obstet Gynaecol. India. 1991;41(4):492-6.

Singhal P, Singhal AK. The fetomaternal outcome in premature rupture of membranes. Obstet Gynecol Today. 2002;10:585.

Raghavan SS. Endocervical prostaglandin E2 (PGE2) gel in premature rupture of membranes. J Obstet Gynecol India. 2001;51:122.

Uma S, Nisha S, Shikha S. A prospective analysis of etiology and outcome of preterm labour. J Obstet Gynecol India. 2007;57(1):48-52.

Naeye R, Peters E. Causes and consequences of premature rupture of fetal membranes. Lancet. 1980;1:192-4.

Lin MG, Nuthalapaty FS, Carver AR, Case AS, Ramsey PS. Misoprostol for labor induction in women with term premature rupture of membranes: a meta-analysis. Obstet Gynecol. 2005;106(3):593-601.

Ray DA, Garite TJ. Prostaglandin E2 for induction of labor in patients with premature rupture of membranes at term. Am J Obstet Gynecol. 1992;166(3):836-43.

Gaikwad BH, Maskar RP. Study of maternal and perinatal outcome in premature rupture of membrane at term pregnancy. J Evol Med Dent Sci. 2016;5(37):2226-9.

Padmaja J, Swarupa K. Maternal and perinatal outcome in premature rupture of membranes at term pregnancy. Int Arch Integ Med. 2018;5(4):87-91.

Devi A, Rani R. Premature rupture of membranes- a clinical study. J Obstet Gynecol India. 1996;46:63.

Seaward PG, Hannah ME, Myhr TL, Farine D, Ohlsson A, Wang EE, et al. International multicenter term PROM study: evaluation of predictors of neonatal infection in infants born to patients with premature rupture of membranes at term. Am J Obstet Gynecol. 1998;179(3):635-9.