A retrospective study on endometrial patterns in abnormal uterine bleeding
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20221936Keywords:
Endometrium, Histopathology, Curettings, BleedingAbstract
Background: To determine the type of endometrial patterns of the different age categories of women who presented as a case of abnormal uterine bleeding.
Methods: This is a retrospective study conducted on 105 patients who presented with abnormal uterine bleeding who underwent fractional curettage in our hospital. The data on their age, presenting complaints, and comorbidities of all the women were collected. The patterns of endometrial changes were studied and classified.
Results: The most common histopathological findings were anovulatory shedding (34.3%) and irregular shedding (18.1%). The other findings include irregular ripening, papillary endocervicitis, endocervicitis, pill endometrium, atrophic endometrium, squamous metaplasia, and endometrial hyperplasia. The most common malignant change seen was endometrioid carcinoma which was seen in women over 40 years of age.
Conclusions: Histopathological examination of the endometrium shows a clear-cut differentiation between physiological and malignancy changes in the endometrium. Hence, endometrial sampling is considered the golden tool for accurate analysis of the endometrium.
References
Munro MG, Critchley HO, Broder MS, Fraser IS; FIGO Working Group on Menstrual Disorders. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet. 2011;113(1): 3-13.
Yilmaz E, Yilmaz Z, Cakmak B, Karsli MF, Gultekin IB, Guneri Dogan N, Kara OF, Kucukozkan T. Nausea and Vomiting in Early Pregnancy of Adolescents: Relationship with Depressive Symptoms. J Pediatr Adolesc Gynecol. 2016;29(1): 65-8.
Yalamati P, Bhongir AV, Betha K, Verma R, Dandge S. Relationship of serum uric acid, serum creatinine and serum cystatin C with maternal and fetal outcomes in rural Indian pregnant women. Int J Reprod Contracept Obstet Gynecol. 2015;4(5):1505-10.
Kayastha S. Study of endometrial tissue in dysfunctional uterine bleeding. Nepal Med Coll J. 2013;15(1):27-30.
Afghan S, Yasmeen A. Abnormal uterine bleeding (AUB): a clinicopathological study of 150 cases. Ann Pak Inst Med Sci. 2013;9(4):201-4.
Talukdar B, Mahela S. Abnormal uterine bleeding in perimenopausal women: Correlation with sonographic findings and histopathological examination of hysterectomy specimens. J Mid-life Health. 2016; 7(2):73.
Jaiswal J, Jaiswal A, Mishra R. A study on relationship of endometrial thickness and abnormal uterine bleeding in perimenopausal women. J South Asian Feder Menopause Soc. 2018;6(2):106-111.
Kotdawala P, Kotdawala S, Nagar N. Evaluation of endometrium in peri-menopausal abnormal uterine bleeding. J Midlife Health. 2013;4:16-21.
Subhankar D, Barunoday C, Rejaul K, Ranen KA, Pradip KM, Tarun KG. Abnormal uterine bleeding in perimenopausal age: Diagnostic options and Accuracy. J Obstet Gynecol India. 2011;61(2): 189-94.
Revel A, Shushan A. Investigation of the infertile couple: hysteroscopy with endometrial biopsy is the gold standard investigation for abnormal uterine bleeding. Hum Reprod. 2002;17(8):1947-9.
