Published: 2017-01-05

A comparative study of antepartum and postpartum eclampsia at a tertiary care centre

Shobha Bembalgi, Vishal Kamate, Samskruti Shetty


Background: Hypertensive disorders complicate 5 to 10 percent of all pregnancies. Eclampsia is one of the dreaded complications of preeclampsia and remains one of the leading causes of maternal deaths in our country. The incidence of post-partum eclampsia is on the rise. Our aim was to study the incidence, demographical factors, and clinical profile associated complications, perinatal and maternal outcomes in pregnancies complicated with antepartum and postpartum eclampsia and compare between the two groups.

Methods: A prospective study was done of all pregnancies complicated with antepartum and postpartum eclampsia over a 10 month period from January 2014 to October 2014 managed at Karnataka institute of medical sciences, Hubli. The results were tabulated and analyzed.

Results: Incidence of antepartum eclampsia was 1.19% and postpartum eclampsia 0.31% amongst the patients delivered in Karnataka institute of medical science, Hubli. Average age of the patients was 24.1 years in the antepartum group and 22.7 yrs in postpartum group. Both antepartum and postpartum eclampsia was most commonly seen in primi gravidas. Though both the types of eclampsias were most commonly seen in term patients, preterm patients had a higher incidence of postpartum eclampsia. Majority of the patients of antepartum eclampsia had mild hypertension whereas postpartum eclampsia patients had mostly severe hypertension. Headache was the most common prodormal symptom in both groups. Neonatal mortality was higher in the postpartum group (44%), whereas maternal mortality was higher in the antepartum group (16.1%).

Conclusions: Incidence of eclampsia cases is high in tertiary care centres. Eclampsia is still one of the leading causes of maternal deaths in our country. Maternal and periantal mortality is high in both antepartum and postpartum eclampsia cases.  The incidence of postpartum eclampsia is significant. Patients with preeclampsia and eclampsia should be closely monitored post natally and measures should be taken to prevent postpartum eclampsias.


Ante partum eclampsia, Postpartum eclampsia, Preeclampsia, Maternal mortality, Perinatal mortality

Full Text:



Nadkarni J, Bahl J, Parekh P. Perinatal Outcome in Pregnancy Associated Hypertension. Indian Pediatrics. 2001;38:174-8.

Anne BW, Audrey FS, Jason H, Hani KA. Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004. Am J Hypertens. 2008:21(5):521-6.

Duley L. Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean. Br J Obstet Gynecol. 2005;99:547-53.

Sibai BM. Diagnosis, prevention and management of eclampsia. Obstetr Gynecol. 2005;105(2):402-10.

Deepika P, Banashree D, Paramita H, Shilpa. Maternal and perinatal outcome in eclampsia and factors affecting the outcome: a study in North Indian population. Int J Reprod Contracept Obstet Gynecol. 2014;3(2):347-51.

Sunita TH, Rathnamala MD. Eclampsia in a teaching hospital: incidence, clinical profile and response to magnesium sulphate by Zuspan’s regimen. IOSR J Dent Med Sci. 2013;4(2):01-5.

Swain S, Ojha KN. Maternal and Perinatal mortality due to eclampsia. Indian Pediatr. 1993;30:771-3.

Rajasri GY, Jaju PB, Vanishree M. Eclampsia and perinatal outcome: a retrospective study in a teaching hospital. J Clin Diagn Res. 2011;5(5):1056-9.

Leitch CR, Cameron AD, Walker JJ. The changing pattern of eclampsia over a 60-year period. Br J Obstet Gynaecol. 1997;104:917-22.

WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. 2011. Available at Accessed on 25 April 2016.

Tranquilli AL, Dekker G, Magee L, Roberts J, Sibai BM, Steyn W, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP. Pregnancy Hypertens. 2014;4:97-104.

Sawhney H, Aggarwal N, Biswas R, Vasishta K, Gopalan S. Maternal mortality associated with eclampsia and severe preeclampsia of pregnancy. J Obstet Gynaecol Res. 2000;26(5):351-6.

Jennifer AH, Sarka L, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Pract Res Clin Obstet Gynaecol 2011;25:391-403.

Watson DM, Sibai BM, Shaver DC, Dacus JV, Anderson GD. Late postpartum eclampsia. An update. Southern Med J. 1983;76:(12):1487-9.

Kaur P. A clinical study of eclampsia in a referral hospital. J South Asian Feder Obster Gynaecol. 2012;4(2):113-5.

Neelam R, Yogendra SV, Geeta A. Comparative study of eclamptic and non-eclamptic convulsive disorders in pregnancy. Sch J App Med Sci. 2014;(5A):1559-64.

Pradeep MR, Lalitha S. retrospective study of eclampsia in a teaching hospital. Intern J Recent Trends Sci Tech. 2013;8(3):171-3.

Choudhary P. Eclampsia: a hospital based retrospective study. Kathmandu Uni Med J. 2003;1(4):237-41.

Anuja B, Sayali K, Sunita G, Anjali K, Sulabha J, Savita S. Eclampsia: maternal and fetal outcome. J South Asian Feder Obster Gynaecol. 2013;5(1):19-21.

Malay S, Sanjay B, Sajal KM, Sandhya D, Dibyendu R, Jaydeb M, et al. Maternal mortality associated with eclampsia in an Indian Medical College: a four year retrospective study. J Med Medic Sci. 2013;4(10):394-8.

Savita RS, Deepika, Anshu, Smiti N. Maternal and perinatal outcome in severe preeclampsia and eclampsia. J South Asian Feder Obster Gynaecol. 2009;1(3):25-8.

Aagaard-Tillery KM, Belfort MA. Eclampsia morbidity, mortality and management. Clin Obstetr Gynecol. 2005;48:12-20.