DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20220014

A comparative study to evaluate pregnancy related issues among women aged 35 years old and beyond

Heena Mir, Neha Mahajan

Abstract


Background: The pregnancy complications associated with women over 35 years of age are becoming more frequent. Late or too late remains the thread bearing discussion these days. Multiple studies have reported that women with 35 years of age or beyond are more vulnerable to develop obstetric complications. The present study has been conducted to reckon the strength of the association between maternal age and obstetric issues pertaining to women.

Methods: This prospective study considered 217 single consecutive pregnancies which were divided into two groups based on age of patients. Group A consists of 163 pregnant women aged < 35 years and group B consists of 54 pregnant patients aged ≥35 years. The study was conducted at government medical college, Lala-Ded, and hospital Srinagar.

Results: In spite of the underlying mechanisms, rigorous statistical analysis revealed the negative impact of extreme maternal ages on pregnancy. We found a significant difference between group A and group B with respect to early pregnancy loss, C-section, antepartum, intrapartum and postpartum complications (p<0.001).

Conclusions: Evidently, it was demonstrated that women aging 35 years or above are more vulnerable to develop multiple intrapartum and postpartum complications than younger women in group B.


Keywords


Antepartum complication, Ostpartum complication, Placenta previa, Assisted conception

Full Text:

PDF

References


Salihu HM, Shumpert MN, Slay M, Kirby RS, Alexander GR. Childbearing beyond maternal age 50 and fetal outcomes in the United States. Obstet Gynecol. 2003;102(5 Pt 1):1006-14.

Hansen JP. Older maternal age and pregnancy outcome: A review of the literature. Obstet Gynecol Surv. 1986;41:726-42.

Carolan MC. Towards understanding the concept of risk for pregnant women: some nursing and midwifery implications. J Clin Nurs. 2009;18(5):652-8.

Shimrit SY, Amalia l, Arnon W. A significant linear association exists between advanced maternal age and adverse perinatal outcome. Arch Gynecol Obstet. 2011;283(4):755-9.

Yogev Y, Melamed N, Haroush B. Pregnancy outcome at extremely advanced maternal age. Am J Obstet Gynecol. 2010;203:558:e1-7.

Ales KL, Druzin ML, Santini DL. Impact of advanced maternal age on the outcome of pregnancy. Surg Gynecol Obstet. 1990;171:209-16.

Pawde Anuya A, Kulkarni Manjiri P, Jyothi U. Pregnancy in women aged 35 years and above: a prospective observational study. J Obstetr Gynecol India. 2015;65(2):93-6.

Leridon H. Can assisted reproductive technology compensate for the natural decline in fertility with age? A model assessment. Hum Reprod. 2004;19:1548-53.

Delbaere I, Verstraelen H, Goetgeluk S. Pregnancy outcome in primiparae of advanced maternal age. EJOG. 2007;135:41-6.

Jacobsson B, Ladfors L, Milsom I. Advanced maternal age and adverse perinatal outcome. Obstet Gynecol. 2004;104:727-33.

Sahu TM, Agarwal A, Das V. Advanced maternal age and obstetric outcome. J Obstet Gynecol India. 2007;57:320-3.

Chibber R. Problems of older maternal age and pregnancy outcome. Bahrain Med Bull. 2004;26:4.

Weerasekera DS, Udugama SG. Pregnancy outcome at 40 and over: a case control study in a developing country. J Obstet Gynecol. 2003;23:625-7.

Luke B, Brown MB. Elevated risk of pregnancy complications and adverse outcomes with increasing maternal age. Hum Repro. 2007;22:1264-72

Carloan MC, Davey M, Biro M. Very advanced maternal age and morbidity in Victoria, Australia: a population-based study. BMC Pregnancy Childbirth. 2013;13:80-9.

Larbi RKT, Buchmann EJ, Matshidze PR. Pregnancy outcome in urban black South African women aged 35 years and older. J Obstet Gynaecol. 2000;20:259-62.