Published: 2021-06-28

A study to establish the prevalence of urinary tract infection in preterm labour

Rashmi Kruthipati, Radhika Chethan, Anitha Gabbalkaje Shiva, Sukanya Suresh, Tejeswini Kolige Krishnappa


Background: Urinary tract infection (UTI) is one of the many etiological factors of preterm labour. Preterm labour is the onset of labour after 28 weeks and before 37 weeks of gestation. Preterm labour is a significant cause for perinatal morbidity and mortality. Hence early diagnosis and management of etiological factors is necessary. The most common bacterial infection encountered during pregnancy is UTIs. Early detection and management of UTIs may effectively prevent complications of preterm labour including preterm birth. Aims and objectives of the study was to estimate the prevalence of UTIs in preterm labour.

Methods: cross sectional study with a total of 250 patients carried out in the department of obstetrics and gynaecology, Vanivilas hospital, BMCRI for a period of 6 moths-Aug 2019-Feb 2020. Patients in preterm labour i.e., cervical dilatation ≥1 cm, cervical effacement ≥80% with true labour pains were included in the study after taken informed consent form the patient. Detailed clinical history including age of patient, level of education, duration of antenatal care, parity, and obstetrical history was taken. Gestational age was calculated by LMP or early ultrasound. General examination, systemic examination and obstetric examination was done. Routine investigations were done along with clean catch midstream urine sample in a sterile container. Two samples were collected: 1st sample for microscopic examination, 2nd sample for culture and sensitivity.

Conclusions: Untreated UTI can be associated with obstetric complications. The most common bacterial infection during pregnancy is UTIs. All women should be screened for UTI at the first antenatal visit. Once diagnosed it should be promptly treated with suitable antibiotic which is sensitive yet safest.


UTI, Preterm labour, Bacteriuria, Urine culture sensitivity, Urine routine

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Gilbert NM, O'brien VP, Hultgren S, Macones G, Lewis WG, Lewis Al. Urinary Tract Infection as a Preventable Cause of Pregnancy Complications: Opportunities, Challenges, and a Global Call to Action Glob Adv Health Med. 2013;2(5):59-69.

Schnarr J, Smaill F. Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. Eur J Clin Investig. 2008;38(2):50-7.

Gratacos E, Torres PJ. Vila J, Alonso PL, Cararach V. Screening and Treatment of Asymptomatic Bacteriuria in Pregnancy Prevent Pyelonephritis. J Infect Dis. 1994;169(6):1390-2.

Sharma P. Acute pyelonephritis in pregnancy: A retrospective study. Aust N Z J Obstet Gynaecol. 2007;47(4):313-5.

Davidson J, Baylis C. Medical Disorders in obstetric Practice 3rd edition, Blackwell Scientific Oxford. 1995;2549.

Lucas MJ, Cunningham FG. Urinary Infection in Pregnancy. Clin Obstet Gynecol. 1993;36(4):855-68.

Beck S, Wojdyla D, Say L. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ. 2010;88:31.

Romero R, Gomez R, Chaiworapongsa T. The role of infection in preterm labour and delivery. Paediatr Perinat Epidemiol. 2001;15(2):41-56.

Lockwood CJ. Predicting premature delivery-no easy task. N Eng J Med. 2002;346:282-4.

Chhabra S, Patil N. Study of factors causing and arresting preterm labour. J Obstet Gynecol India. 2001;51:99-103.

Keelan JA, Blumenstein M, Helliwell RJA. Cytokines, prostaglandins and parturition-a review. Placenta. 2003;17:S33-46.

Romero R, Espinoza J, Chaiworapongsa T. Infection and prematurity and the role of preventive strategies. Semin Neonatol. 2002;7:259-74.

Goldenberg RL, Hauth JC, Andrew WW. Intrauterine infection and preterm delivery. N Eng J Med. 2000;342:1500-7.

Pandey K, Bhagoliwal A, Gupta N, Katiyar G. Predictive value of various risk factors for preterm labour. J Obstet Gynecol India. 2010;60:141-5.

McPheeters ML, Miller WC, Hartmann KE. The epidemiology of threatened preterm labor: a prospective cohort case. Am J Obstet Gynecol. 2005;192(4):1325-9.

Romero R, Oyarzun E, Mazor M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Obstet Gynecol. 1989;73:576-642.