DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20211527

Outcomes and analysis of fetomaternal elements and delivery strategies with neonatal respiratory distress

Sambedna ., Amit Kumar, Rita Chakore

Abstract


Background: Perinatal asphyxia is one of the most important causes of morbidity and mortality in neonates. Perinatal asphyxia occurs in association with different maternal and fetal determinants. However, the relation of associated factors with perinatal asphyxia is not well studied. The aim of this study was to determine the association of maternofetal factors and mode of delivery with perinatal asphyxia in a tertiary care centre.

Methods: This was a retrospective comparative study conducted in department of OBG in tertiary care health centre. A total 200 newborns were selected for study out of which100 newborns were with asphyxia at birth as study group and 100 non asphyxiated newborns were taken as control group. Maternal factor like age, parity, gestational age and fetal factor like weight at birth and mode of delivery were studied to established association on perinatal asphyxia.

Results: Maternal factor like age, parity, gestational age had not significant relationship with perinatal asphyxia. Maximum number of babies delivered in both control and the study group were in the range of 2.6 to 3kg.In this study birth weight did not have significant relationship with perinatal asphyxia. Proportions of LSCS was comparatively higher in the study group though. The delivery mode did not have any statistically significant influence on the newborns affliction with birth asphyxia (p>0.05).

Conclusions: Findings of this study highlight the need for the better obstetrical care and awareness of the possible presence of the risk factors of PNA (perinatal asphyxia) among mothers and fetus, so that the incidence and complications of PNA could be prevented or at least appropriately managed. It can reduce the high incidence of morbidity and mortality due to birth asphyxia.

 


Keywords


Birth asphyxia, Delivery mode, Maternofetal factor

Full Text:

PDF

References


World Health Organization and Others, Guidelines on Basic Newborn Resuscitation. World Heal Organ. 2012.

Lincetto O. Birth Asphyxia- Summary of the Previous Meeting and Protocol Overview. 2007.

WHO, World Health Statistics, WHO, Geneva, Switzerland. 2015.

Lei H, Peeling J. Effect of temperature on the kinetics of lactate production and clearance in a rat model of forebrain ischemia. Biochem Cell Biol. 1998;76(2-3):503-9.

Penrice J, Lorek A, Cady EB, Amess PN, Wylezinska M, Cooper CE, et al. Proton magnetic resonance spectroscopy of the brain during acute hypoxia-ischemia and delayed cerebral energy failure in the newborn piglet. Pediatr Res. 1997;41(6):795-802.

Lei H, Berthet C, Hirt L, Gruetter R. Evolution of the neurochemical profile after transient focal cerebral ischemia in the mouse brain. J Cereb Blood Flow Metab. 2009;29(4):811-9.

Ghosh B, Mittal S, Kumar S, Dadhwal V. Prediction of perinatal asphyxia with nucleated red blood cells in cord blood of newborns. Int J Gynaecol Obstet. 2003;81(3):267-71.

Saracouglu F, Sahin I, Eser E, Gol K, Turkkani B. Nucleated red blood cells as a marker in acute and chronic fetal asphyxia. Int J Gynecol Obstet. 2000;71(2):113-8.

Qaiser DH, Sandila MP, Kazmi T, Ahmed ST. Influence of maternal factors on hematological parameters of healthy newborns of Karachi. Pak J Physol. 2009;5(2):34-7.

Boskabadi H, Afshari JT, Ghayour-Mobarhan M, Maamouri GH, Shakeri MT, Sahebkar A. Association between serum interleukin-6 levels and severity of perinatal asphyxia. Asian Biomedicine. 2010;4(1):79-85.

Clifford SH. High risk pregnancy I. Prevention of prematurity. The sin qua non for reduction in mental retardation and other neurological disorders. New Eng J Med. 1964;271(19):243-2.

Macdonald HM, Muligan JC, Allen AC, Taylor PM. Neonatal asphyxia I. Relationship of obstetric and neonatal complication to neonatal mortality in 38,405 consecutive deliveries Y Pediatr. 1980;96(5):898-902.

Papa D, Jyotsna P, Ashok BB. Cord blood nucleated red blood cell count-a marker of fetal asphyxia. J Obstet Gynecol India. 2008;58(1):45-4.

Pitsawong C. Risk Factors Associated with Bir th Asphyxia in Phramongkutklao Hospital. Thai J Obstet Gynaecol. 2011;19(4):165-71.

Solayman M, Hoque S, Akber T, Islam MI, Islam MA. Prevalence of Perinatal Asphyxia with Evaluation of Associated Risk Factors in a Rural Tertiary Level Hospital. KYAMC J. 2017;8(1):43-8.

Tabassum F, Rizvi A, Ariff S, Soofi S, Bhutta ZA. Risk Factors Associated with Birth Asphyxia in Rural District Matiari, Pakistan: A Case Control Study. Int J Clini Med. 2014;5(21):1430-41.

Batra A, Sengupta A, Kumar A, Bhargava SK. A study of asphyxia neonatorum. Ind J Obstet Gynecol. 1988;38:162-6.

Uzel H, Kelekc S, Devecioglu C, Güneş A, Yolbaş İ, Şen V. Neonatal asphyxia: A study of 210 cases. J Clin and Exp Investi. 2012;3(2):194-8.

Chiabi A, Nguefack S, Evelyne MA, Nodem S, Mbuagbaw L, Mbonda E, Tchokoteu PF. Risk factors for birth asphyxia in an urban health facility in Cameroon. Iran J Child Neuro. 2013;7(3)46-54.

Gupta SK, Sarmah BK, Tiwari D, Shakya A, Khatiwada D. Clinical Profle of Neonates with Perinatal Asphyxia in a Tertiary Care Hospital of Central Nepal. J the Nepal Med Association. 2014;52(12):1005-9.

Ilah BG, Aminu MS, Musa A, Adelakun MB, Adeniji AO, Kolawole T. Prevalence and risk factors for perinatal asphyxia as seen at a specialist hospital in Gusau, Nigeria. Sub-Saharan Afr J Med. 2015;2(2):64

Kiyani AN, Khushdil A, Ehsan A. Perinatal factors leading to birth asphyxia among term newborns in a tertiary care hospital. Iran J pediat. 2014;24(5):637. PMID: 25793074.

Utomo MT: Risk factors for birth asphyxia. Folia Medica Indonesiana. 2011;47(4):211-4.

Nayeri F, Shariat M, Dalili H, Adam LB, Mehrjerdi FZ, Shakeri A. Perinatal risk factors for neonatal asphyxia in Vali-e-Asr hospital, Tehran-Iran. Iran J Reprod Med. 2012;10(2):137.

Harrison MS, Goldenberg RL. Cesarean section in sub-Saharan Africa. Maternal health, neonato and perinato. 2016;2(1):6.