Histopathological features of endometrium in those with symptoms suggestive of female genital tuberculosis

Authors

  • R. Sankareswari Department of Obstetrics and Gynecology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, Pondicherry, India
  • Ramya Sreevarshni Shunmugha Sundharam Department of Obstetrics and Gynecology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, Pondicherry, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20181911

Keywords:

Female genital TB, Endometrial biopsy, Histopathological pattern

Abstract

Background: Histological characteristics of endometrial biopsy material as assessed by light microscopy remain the diagnostic standard for the clinical diagnosis of endometrial pathology. Management of female genital TB is not complete without tissue diagnosis. The aim of the present study was to find out the histopathological pattern of the

endometrium in those with symptoms suggestive of genital tuberculosis.

Methods: A random sample of 200 female OPD patients with symptoms suggestive of FGTB attending to the Obstetrics and Gynaecology OPD in a tertiary care hospital at Ariyur, Puducherry were subjected to endometrial curettage and histological characteristics of endometrial biopsy material was assessed.

Results: Endometrial histopathology revealed proliferative endometrium (60.5%, n=121), secretary endometrium (25.5%, n=51) and menstrual endometrium (9%, n=18) in majority. Chronic endometritis (3%, n=6), Simple hyperplasia without atypia (1%, n=2), atrophic (0.5%, n=1) and inert endometrium (0.5%, n=1) were other abnormalities reported.

Conclusions: Histopathological features of endometrium in those with suggestive symptoms of female genital TB are variable and non-specific.

References

Kumar S. Female genital tuberculosis, In:Sharma SK, Mohan A. (eds) Tuberculosis, 2nd edition Delhi: Jaypee,2009;441-8.

Neonakis IK, Spandidos DA, Petinaki E,Female genital tuberculosis: a review. Cand J Infect Dis. 2011;43:564-72.

Marjorie PG, Holenarasipur RV. Extra pulmonary tuberculosis: An overview. Am Fam Physician. 2005;72:1761-8.

Vithalani N, Udani PM, Vithalani N. A study of 292 autopsies proved cases of tuberculosis. Indian J Tuber. 1982;29:93-7.

Sinha R, Gupta D, Tuli N. genital tract tuberculosis with myometrial involvement. Int J Gyneacol Obstet. 1997;57:191-2.

Puri S, Bansal B. Diagnostic Value of Polymerase Chain Reaction in Female Tuberculosis Leading to Infertility and Conception Rate after ATT. JK Sci J Medi Edu Res. 2009;11:31-3.

WHO | Global tuberculosis report 2014 [Internet]. WHO. [Cited 2015 Sep 11]. Available from: http://www.who.int/tb/publications/global_report/en/

Dhillon SS, Gosewehr JA, Julian TM, Huey J. Genital tuberculosis: Case report and literature review. Wis Med J. 1990;89:14.

Schaefer Kumar S Female genital tuberculosis, In: Sharma SK, Mohan A. Tuberculosis, 2nd edition G: Female genital tuberculosis. Clin Obstet Gynecol. 1976;19:223.

Varma TR. Genital tuberculosis and subsequent fertility. Int J Gynaecol Obstet. 199135:1.

Klein TA, Richmond JA, Mishell DR. Pelvic tuberculosis. Obstet Gynecol. 1976;48:99.

Tripathy SN, Tripathy SN. Endometrial tuberculosis. J Indian Med Assoc. 1987;85:136.

Falk V, Ludviksson K, Agren G. Genital tuberculosis in women: Analysis of 187 newly diagnosed cases from 47 Swedish hospitals during the ten-year period 1968 to 1977. Am J Obstet Gynecol. 1980; 138:933.

Chattopadhyay SK, Sengupta BS, Edrees YB, Al-Meshari AA, The pattern of female genital tuberculosis in Riyadh, Saudi Arabia. Br J Obstet Gynaecol. 1986;93:363.

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Published

2018-04-28

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Original Research Articles